{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T02:55:08Z","timestamp":1768445708257,"version":"3.49.0"},"reference-count":0,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":1461,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HPB Surgery"],"published-print":{"date-parts":[[1996,1]]},"abstract":"<jats:p>Spontaneous liver rupture is uncommon, difficult to diagnose and carries a universally high mortality. It\nhas been well documented to occur as a complication of primary or secondary hepatic malignancy.\nSimilarly, there are 28 cases of ruptured haemangiomata described in the world literature. It is also well\ndescribed in severe pregnancy\u2010induced hypertension and is said to carry a mortality of 18% for patients\ntreated by packing and drainage of the haematoma and 75% for patients treated with liver resection.<\/jats:p><jats:p>Two female patients aged 60 and 61 presented to our accident and emergency department. One had a\nhistory of hypertension only and the other a history of a bleeding diathesis from the lupus anticoagulant.\nBoth presented with hypotension and abdominal pain and both were diagnosed by abdominal CT scan.\nOne was treated with hepatic artery ligation and tamponade and the other with liver resection and\ncorrection of the coagulopathy. Neither had any evidence of a ruptured haemangioma or tumour at\nlaparotomy or on histological examination, and both are alive and well.<\/jats:p><jats:p>The conclusions to be drawn from this review and our own recent experience is that the treatment of\nchoice for ruptured haemangiomata is liver resection and, for rupture during pregnancy, is tamponade\nwith packs and evacuation of the haematoma. Hepatic arteriography and embolisation, if possible, is a\nuseful adjunct. Correction ofany coagulopathy is essential. We can only speculate that the aetiology in our\npatients was uncontrolled hypertension in one and coagulopathy in the other.<\/jats:p>","DOI":"10.1155\/1996\/24016","type":"journal-article","created":{"date-parts":[[2007,9,13]],"date-time":"2007-09-13T09:19:26Z","timestamp":1189675166000},"page":"257-260","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Two Cases of Spontaneous Liver Rupture and Literature Review"],"prefix":"10.1155","volume":"9","author":[{"given":"P. J.","family":"Cozzi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. L.","family":"Morris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1996,1]]},"container-title":["HPB Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/1996\/024016.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/1996\/24016","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T01:13:10Z","timestamp":1723079590000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/1996\/24016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1996,1]]}},"alternative-id":["10.1155\/1996\/24016"],"URL":"https:\/\/doi.org\/10.1155\/1996\/24016","archive":["Portico"],"relation":{},"ISSN":["0894-8569","1607-8462"],"issn-type":[{"value":"0894-8569","type":"print"},{"value":"1607-8462","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,1]]},"assertion":[{"value":"1993-04-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1996-01-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}