{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T05:06:29Z","timestamp":1735707989957,"version":"3.32.0"},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":1683,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Journal of Infectious Diseases and Medical Microbiology"],"published-print":{"date-parts":[[1996,1]]},"abstract":"<jats:p>OBJECTIVE: To assess the prevalence of antibiotic resistance in Canadian intensive care units.<\/jats:p><jats:p>DESIGN: The antimicrobial profiles of 1939 Gram\u2010negative bacilli isolated in 20 Canadian intensive care units were analyzed using a custom designed MicroScan panel.<\/jats:p><jats:p>SETTING: The majority of the hospitals were tertiary care institutions, but some community hospitals were included.<\/jats:p><jats:p>PATIENTS: Adult intensive care unit patients were the sources of isolates.<\/jats:p><jats:p>MAIN RESULTS: <jats:italic>Pseudomonas aeruginosa<\/jats:italic> was the most frequently isolated microorganism overall, with <jats:italic>Escherichia coli<\/jats:italic> the most common initial isolate. Comparison of initial and repeat isolates showed that <jats:italic>P aeruginosa<\/jats:italic> readily acquired resistance to all antibiotic classes except the aminoglycosides. <jats:italic>Enterobacter aerogenes<\/jats:italic> developed resistance to ciprofloxacin and <jats:italic>Enterobacter cloacae<\/jats:italic> demonstrated resistance to all beta\u2010lactam antibiotics except for imipenem on repeat isolation. Other Enterobacteriaceae remained susceptible. Historical comparison with data derived four years previously from 15 of the centres showed increased resistance of <jats:italic>P aeruginosa<\/jats:italic> and <jats:italic>Acinetobacter<\/jats:italic> species to ciprofloxacin while other susceptibility patterns remained stable.<\/jats:p><jats:p>CONCLUSIONS: The prevalence of Gram\u2010negative resistance in Canadian hospitals is less than that reported in surveys done in some other countries, and was relatively stable over four years.<\/jats:p>","DOI":"10.1155\/1996\/812389","type":"journal-article","created":{"date-parts":[[2016,3,15]],"date-time":"2016-03-15T08:05:32Z","timestamp":1458029132000},"page":"34-40","source":"Crossref","is-referenced-by-count":0,"title":["Incidence and Susceptibility of Aerobic Gram\u2010Negative Bacilli from 20 Canadian Intensive Care Units: 1989\u20131993"],"prefix":"10.1155","volume":"7","author":[{"given":"Elizabeth A","family":"Bryce","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W David","family":"Colby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques","family":"Haket","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel W","family":"Poisson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John A","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1995,5,24]]},"container-title":["Canadian Journal of Infectious Diseases and Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjidmm\/1996\/812389.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/1996\/812389","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T05:05:20Z","timestamp":1735621520000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/1996\/812389"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,5,24]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1996,1]]}},"alternative-id":["10.1155\/1996\/812389"],"URL":"https:\/\/doi.org\/10.1155\/1996\/812389","archive":["Portico"],"relation":{},"ISSN":["1712-9532","1918-1493"],"issn-type":[{"type":"print","value":"1712-9532"},{"type":"electronic","value":"1918-1493"}],"subject":[],"published":{"date-parts":[[1995,5,24]]}}}