{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,22]],"date-time":"2025-06-22T05:20:54Z","timestamp":1750569654561},"reference-count":0,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":1095,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Canadian Journal of Gastroenterology and Hepatology"],"published-print":{"date-parts":[[1997,1]]},"abstract":"<jats:p>Acute                             hemorrhage from esophageal varices is a medical emergency;                             despite early diagnosis and treatment the associated                             hospital mortality remains high. The clinical research                             summarized in this paper shows that octreotide has a                             beneficial effect on portal hemodynamics in cirrhotic                             patients. In randomized controlled trials octreotide                             has been effective in halting initial hemorrhage and                             in preventing reoccurrence of bleeding. Somatostatin                             and octreotide appear to be equivalent in terms of therapeutic                             efficacy but octreotide is the less expensive option.                             For suspected variceal bleeding an octreotide infusion                             should be initiated immediately. To prevent further                             bleeding the drug should be continued for two to five                             days after endoscopic variceal ligation.<\/jats:p>","DOI":"10.1155\/1997\/156920","type":"journal-article","created":{"date-parts":[[2016,3,31]],"date-time":"2016-03-31T21:18:55Z","timestamp":1459459135000},"page":"339-343","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Use of Octreotide in the Acute Management of Bleeding Esophageal Varices"],"prefix":"10.1155","volume":"11","author":[{"given":"Daniel C","family":"Sadowski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1997,6]]},"container-title":["Canadian Journal of Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/1997\/156920.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/1997\/156920","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T16:54:08Z","timestamp":1722358448000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/1997\/156920"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1997,1]]}},"alternative-id":["10.1155\/1997\/156920"],"URL":"https:\/\/doi.org\/10.1155\/1997\/156920","archive":["Portico"],"relation":{},"ISSN":["2291-2789","2291-2797"],"issn-type":[{"type":"print","value":"2291-2789"},{"type":"electronic","value":"2291-2797"}],"subject":[],"published":{"date-parts":[[1997,1]]},"assertion":[{"value":"1996-08-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1997-01-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1997-06-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}