{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T15:12:55Z","timestamp":1789225975539,"version":"build-2803163510"},"reference-count":0,"publisher":"Hindawi Limited","issue":"5","license":[{"start":{"date-parts":[[1997,1,1]],"date-time":"1997-01-01T00:00:00Z","timestamp":852076800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Journal of Gastroenterology"],"published-print":{"date-parts":[[1997]]},"abstract":"<jats:p><jats:italic>Helicobacter pylori<\/jats:italic> infection is an important cause of peptic ulcer disease and chronic gastritis. Infection with this bacterium stimulates the production of immunoglobulin (Ig) G antibody. Salivary IgG antibody tests to detect <jats:italic>H pylori<\/jats:italic> infection offer a convenient and noninvasive method of diagnosis. To evaluate an IgG salivary antibody kit, saliva was collected from 157 out-patients with dyspepsia referred for endoscopy to a tertiary centre. A salivary IgG ELISA antibody assay was performed using the Helisal <jats:italic>Helicobacter pylori<\/jats:italic> (IgG) assay kit, and at least four gastric biopsies were obtained. <jats:italic>H pylori<\/jats:italic> infection was confirmed by demonstration of the organism on Warthin-Starry silver stain (sensitivity 85%, specificity 55%). The prevalence of infection with <jats:italic>H pylori<\/jats:italic> was 30%. When the analysis was redone, excluding those treated with eradication therapy, the results were similar (sensitivity 86%, specificity 58%). The positive predictive value of the assay was 45% and the negative predictive value was 90%. Despite the ease of sampling, the assay used has limited diagnostic utility, lacking the predictive value to indicate which patients referred with dyspeptic symptoms to a tertiary care setting are infected with <jats:italic>H pylori<\/jats:italic>.<\/jats:p>","DOI":"10.1155\/1997\/294081","type":"journal-article","created":{"date-parts":[[2016,3,31]],"date-time":"2016-03-31T17:20:01Z","timestamp":1459444801000},"page":"437-440","source":"Crossref","is-referenced-by-count":17,"title":["Evaluation of Salivary Antibodies to Detect Infection with <i>Helicobacter pylori<\/i>"],"prefix":"10.1155","volume":"11","author":[{"given":"Mark B","family":"Loeb","sequence":"first","affiliation":[{"name":"Departments of Laboratory Medicine, Pathology and Gastroenterology, McMaster University Medical Centre, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert H","family":"Riddell","sequence":"additional","affiliation":[{"name":"Departments of Laboratory Medicine, Pathology and Gastroenterology, McMaster University Medical Centre, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cindy","family":"James","sequence":"additional","affiliation":[{"name":"Departments of Laboratory Medicine, Pathology and Gastroenterology, McMaster University Medical Centre, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Hunt","sequence":"additional","affiliation":[{"name":"Departments of Laboratory Medicine, Pathology and Gastroenterology, McMaster University Medical Centre, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona M","family":"Smaill","sequence":"additional","affiliation":[{"name":"Departments of Laboratory Medicine, Pathology and Gastroenterology, McMaster University Medical Centre, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","container-title":["Canadian Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/1997\/294081.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/1997\/294081.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,12,20]],"date-time":"2016-12-20T16:04:58Z","timestamp":1482249898000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cjgh\/1997\/294081\/abs\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1997]]}},"alternative-id":["294081"],"URL":"https:\/\/doi.org\/10.1155\/1997\/294081","relation":{},"ISSN":["0835-7900"],"issn-type":[{"value":"0835-7900","type":"print"}],"subject":[],"published":{"date-parts":[[1997]]}}}