{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T15:52:45Z","timestamp":1760889165979},"reference-count":0,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":1095,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Canadian Journal of Gastroenterology and Hepatology"],"published-print":{"date-parts":[[1997,1]]},"abstract":"<jats:p><jats:bold>OBJECTIVE:<\/jats:bold>                             To study the clinical presentation, endoscopic features                             and prevalence of <jats:italic>Helicobacter pylori<\/jats:italic> in duodenal ulcer                             (DU) patients in southern Saudi Arabia, located 3150                             m above sea level, and to compare results with those                             from low altitude regions of the Kingdom.<\/jats:p><jats:p><jats:bold>METHODS:<\/jats:bold> Prospective study of patients with proven                             DU referred for upper gastrointestinal endoscopy at                             Asir Central Hospital, Abha, southern Saudi Arabia over                             an 18\u2010month period.<\/jats:p><jats:p><jats:bold>RESULTS:<\/jats:bold> Of 126 patients with proven DU, 72%                             were men and mean age was 40.4 years (range 18 to 68).                             Twenty\u2010eight per cent were smokers and only 5% used                             nonsteroidal anti\u2010inflammatory drugs. Thirty\u2010eight patients                             (30%) presented with hematemesis or melena, and the                             majority had a single ulcer. Nineteen per cent of patients                             with dyspepsia had DU and 96% had <jats:italic>H pylori<\/jats:italic>. These                             results are comparable with those reported from the                             low altitude, warmer regions of Saudi Arabia.<\/jats:p><jats:p><jats:bold>CONCLUSIONS:<\/jats:bold> Age of patients and the male:female                             ratio were similar to those in developing countries.                             The frequency of smoking is lower than in western countries                             and no patient in this report consumed alcohol. High                             altitude did not affect the prevalence of DU or the                             frequency of <jats:italic>H pylori<\/jats:italic> because the results were                             comparable with those from the low altitude areas of                             the Kingdom of Saudi Arabia and other lowland developing                             countries. Although great socioeconomic changes have                             increased the incidence of heart disease, the patterns                             of DU and <jats:italic>H pylori<\/jats:italic> infection assume those in                             developing nations.<\/jats:p>","DOI":"10.1155\/1997\/589701","type":"journal-article","created":{"date-parts":[[2016,3,31]],"date-time":"2016-03-31T21:21:49Z","timestamp":1459459309000},"page":"313-316","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Duodenal Ulcer and <i>Helicobacter pylori<\/i> Infection at High Altitude: Experience from Southern Saudi Arabia"],"prefix":"10.1155","volume":"11","author":[{"given":"M El Bagir K","family":"Ahmed","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BA","family":"Al-Knawy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AH","family":"Al-Wabel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AK","family":"Foli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1997,6]]},"container-title":["Canadian Journal of Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/1997\/589701.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/1997\/589701","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T16:54:05Z","timestamp":1722358445000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/1997\/589701"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1997,1]]}},"alternative-id":["10.1155\/1997\/589701"],"URL":"https:\/\/doi.org\/10.1155\/1997\/589701","archive":["Portico"],"relation":{},"ISSN":["2291-2789","2291-2797"],"issn-type":[{"type":"print","value":"2291-2789"},{"type":"electronic","value":"2291-2797"}],"subject":[],"published":{"date-parts":[[1997,1]]},"assertion":[{"value":"1996-06-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1996-10-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1997-06-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}