{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T14:40:06Z","timestamp":1722523206002},"reference-count":0,"publisher":"Wiley","issue":"D","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":316,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Canadian Journal of Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2000,1]]},"abstract":"<jats:p>Complications of portal hypertension\nare the Achilles heel of end\u2010stage liver disease. Although\ninitially developed in the 1960s, transjugular intrahepatic portosystemic\nshunts (TIPS) have recently gained popularity for decompressing\nthe portal vein in patients with portal hypertension.\nThe main indications for TIPS are the treatment of variceal hemorrhage\nunresponsive to endoscopic treatment and refractory ascites.\nAlthough several other applications for TIPS have been\nreported, they have not been tested in controlled trials. TIPS are\nnot appropriate as initial therapy for variceal hemorrhage and ascites.\nDue to the virtually universal development of TIPS stenosis\nin the majority of patients, careful monitoring of stent patency is\nrequired. Several complications of TIPS are recognized, some of\nwhich are potentially fatal. Consequently, careful patient selection\nfor TIPS is of paramount importance. Until further clinical\ntrials become available, TIPS should be considered as a therapeutic\noption for the treatment of refractory variceal hemorrhage and\nrefractory ascites in selected patients.<\/jats:p>","DOI":"10.1155\/2000\/309539","type":"journal-article","created":{"date-parts":[[2016,5,15]],"date-time":"2016-05-15T21:00:45Z","timestamp":1463346045000},"update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Are TIPS Tops in the Treatment of Portal Hypertension? A Review on the Use and Misuse of Transjugular Intrahepatic Portosystemic Shunts"],"prefix":"10.1155","volume":"14","author":[{"given":"Richard K","family":"Sterling","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arun J","family":"Sanyal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1999,2,19]]},"container-title":["Canadian Journal of Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2000\/309539.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2000\/309539","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T14:13:21Z","timestamp":1722521601000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2000\/309539"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,2,19]]},"references-count":0,"journal-issue":{"issue":"D","published-print":{"date-parts":[[2000,1]]}},"alternative-id":["10.1155\/2000\/309539"],"URL":"https:\/\/doi.org\/10.1155\/2000\/309539","archive":["Portico"],"relation":{},"ISSN":["2291-2789","2291-2797"],"issn-type":[{"type":"print","value":"2291-2789"},{"type":"electronic","value":"2291-2797"}],"subject":[],"published":{"date-parts":[[1999,2,19]]},"assertion":[{"value":"1999-02-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1999-02-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"1999-02-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}