{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T08:05:21Z","timestamp":1775030721063,"version":"3.50.1"},"reference-count":0,"publisher":"Hindawi Limited","issue":"9","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Journal of Gastroenterology"],"published-print":{"date-parts":[[2000]]},"abstract":"<jats:p>OBJECTIVES: To study the indications for liver transplantation among British Columbia\u2019s First Nation population.<\/jats:p><jats:p>MATERIALS AND METHODS: A retrospective analysis of the British Columbia Transplant Society\u2019s database of Aboriginal and non-Aboriginal liver transplant recipients from 1989 to 1998 was undertaken. For primary biliary cirrhosis (PBC), the transplant assessment database (patients with and without transplants) was analyzed using a binomial distribution and compared with published census data regarding British Columbia\u2019s proportion of Aboriginal people.<\/jats:p><jats:p>RESULTS: Between 1989 and 1998, 203 transplantations were performed in 189 recipients. Fifteen recipients were Aboriginal (n=15; 7.9%). Among all recipients, the four most frequent indications for liver transplantation were hepatitis C virus (HCV) infection (n=57; 30.2%), PBC (n=34; 18.0%), alcohol (n=22; 11.6%) and autoimmune hepatitis (n=14; 7.4%). Indications for liver transplantation among Aboriginal people were PBC (n=8; 53.3%; P&lt;0.001 compared with non-Aboriginal people), autoimmune hepatitis (n=4; 26.67%; P=0.017), acute failure (n=2; 13.3%) and HCV (n=1). Among all patients referred for liver transplantation with PBC (n=43), 29 (67.44%) were white and 11 (25.6%) were Aboriginal. A significant difference was found between the proportion of Aboriginal people referred for liver transplantation and the proportion of Aboriginal people in British Columbia (139,655 of 3,698,755 [3.8%]; 1996 Census, Statistics Canada) (P&lt;0.001).<\/jats:p><jats:p>CONCLUSIONS: Aboriginal people in British Columbia are more likely to be referred for liver transplantation with a diagnosis of PBC but are less likely to receive a liver transplant because of HCV or alcohol than are non-Aboriginal people.<\/jats:p>","DOI":"10.1155\/2000\/907463","type":"journal-article","created":{"date-parts":[[2016,4,14]],"date-time":"2016-04-14T16:58:01Z","timestamp":1460653081000},"page":"775-779","source":"Crossref","is-referenced-by-count":8,"title":["Indications for Liver Tranplantation in British Columbia\u2019s Aboriginal Population: A 10-Year Retrospective Analysis"],"prefix":"10.1155","volume":"14","author":[{"given":"Eric M","family":"Yoshida","sequence":"first","affiliation":[{"name":"Department of Medicine, the University of British Columbia and the British Columbia Transplant Society, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadine R","family":"Caron","sequence":"additional","affiliation":[{"name":"Department of Surgery, the University of British Columbia and the British Columbia Transplant Society, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrzej K","family":"Buczkowski","sequence":"additional","affiliation":[{"name":"Department of Surgery, the University of British Columbia and the British Columbia Transplant Society, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura T","family":"Arbour","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics, the University of British Columbia and the British Columbia Transplant Society, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles H","family":"Scudamore","sequence":"additional","affiliation":[{"name":"Department of Surgery, the University of British Columbia and the British Columbia Transplant Society, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Urs P","family":"Steinbrecher","sequence":"additional","affiliation":[{"name":"Department of Medicine, the University of British Columbia and the British Columbia Transplant Society, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siegfried R","family":"Erb","sequence":"additional","affiliation":[{"name":"Department of Medicine, the University of British Columbia and the British Columbia Transplant Society, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen W","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Surgery, the University of British Columbia and the British Columbia Transplant Society, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","container-title":["Canadian Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2000\/907463.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2000\/907463.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,23]],"date-time":"2016-08-23T16:13:50Z","timestamp":1471968830000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/cjgh\/2000\/907463\/abs\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000]]},"references-count":0,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2000]]}},"alternative-id":["907463"],"URL":"https:\/\/doi.org\/10.1155\/2000\/907463","relation":{},"ISSN":["0835-7900"],"issn-type":[{"value":"0835-7900","type":"print"}],"subject":[],"published":{"date-parts":[[2000]]}}}