{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T05:06:30Z","timestamp":1735707990455,"version":"3.32.0"},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Canadian Journal of Infectious Diseases and Medical Microbiology"],"published-print":{"date-parts":[[2003,1]]},"abstract":"<jats:p>BACKGROUND: There has never been a cross\u2010Canada surveillance project to determine the rate of <jats:italic>Legionella<\/jats:italic> species as a cause of community\u2010acquired pneumonia requiring hospitalization and to determine whether there are any regional differences in the rates of Legionnaires\u2032 disease in Canada. Anecdotally, Legionnaires\u2032 disease is thought to be uncommon in Western Canada.<\/jats:p><jats:p>METHODS: From January, 1996 through to October 31, 1997, a prospective study of the etiology of community acquired pneumonia requiring admission to 15 tertiary care hospitals in eight Canadian provinces was conducted. A urine sample from each patient was tested for <jats:italic>Legionella pneumophila<\/jats:italic> serogroup 1 antigen using a commercially available ELISA assay. A culture of sputum or other respiratory specimens for Legionellaceae was carried out at the discretion of the attending physician. Two hundred thirty\u2010four patients had acute and 6\u2010week convalescent serum samples tested for antibodies to <jats:italic>L pneumophila<\/jats:italic> serogroups 1 through 6 using an ELISA method.<\/jats:p><jats:p>RESULTS: 28 of the 850 patients (3.2%) had Legionnaires\u2032 disease; 18 of 823 (2.1%) were positive for <jats:italic>L pneumophila<\/jats:italic> serogroup 1 by urinary antigen testing. The rate of Legionnaires\u2032 disease, based on urinary antigen, at the Halifax site was higher than that at the other sites (seven of 163 patients versus 11 of 660 [P=0.04]). Of the 28 cases of Legionnaires\u2032 disease identified using all methods, 11 of 277 patients (3.9%) were enrolled from Western provinces versus 17 of 573 patients (2.9%) from Eastern provinces (P=nonsignificant).<\/jats:p><jats:p>CONCLUSIONS: Legionnaires\u2032 disease is just as common in Western as in Eastern Canada. <jats:italic>L pneumophila<\/jats:italic> serogroup 1 may be more common in Halifax than at the other sites studied.<\/jats:p>","DOI":"10.1155\/2003\/951567","type":"journal-article","created":{"date-parts":[[2016,3,15]],"date-time":"2016-03-15T13:53:29Z","timestamp":1458050009000},"page":"154-158","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Legionnaires\u2032 Disease \u2010 Results of a Multicenter Canadian Study"],"prefix":"10.1155","volume":"14","author":[{"given":"Thomas J","family":"Marrie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emidio","family":"de Carolis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor L","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet","family":"Stout","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"the Canadian Community-Acquired Pneumonia Investigators","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,6]]},"container-title":["Canadian Journal of Infectious Diseases and Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjidmm\/2003\/951567.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2003\/951567","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T05:05:08Z","timestamp":1735621508000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2003\/951567"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2003,1]]}},"alternative-id":["10.1155\/2003\/951567"],"URL":"https:\/\/doi.org\/10.1155\/2003\/951567","archive":["Portico"],"relation":{},"ISSN":["1712-9532","1918-1493"],"issn-type":[{"type":"print","value":"1712-9532"},{"type":"electronic","value":"1918-1493"}],"subject":[],"published":{"date-parts":[[2003,1]]},"assertion":[{"value":"2002-09-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2003-02-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2003-06-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}