{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T22:32:09Z","timestamp":1740177129089,"version":"3.37.3"},"reference-count":0,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Canadian Respiratory Journal"],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:p>Idiopathic nontransplant\u2010related childhood bronchiolitis obliterans  is an uncommon disease. Most patients present with chronic recurrent  dyspnea, cough and wheezing, which are also features of asthma,  by far a much more common condition. The present case study  reports on a six\u2010year\u2010old girl who presented to a tertiary care centre  with recurrent episodes of respiratory distress on a background of  baseline tachypnea, chronic hypoxemia and exertional dyspnea. Her  past medical history revealed significant lung disease in infancy,  including respiratory syncytial virus bronchiolitis and repaired gastroesophageal  reflux. She was treated for \u2032asthma exacerbations\u2032  throughout her early childhood years. Bronchiolitis obliterans was  subsequently diagnosed with an open lung biopsy. She did not have  sustained improvement with systemic corticosteroids, hydroxychloroquine  or clarithromycin. Cardiac catheterization confirmed the presence  of secondary pulmonary hypertension. Treatment options  remain a dilemma for this patient because there is no known effective  treatment for this condition, and the natural history is not well  understood. The present case demonstrates the need for careful  workup in \u2032atypical asthma\u2032, and the urgent need for further research  into the rare lung diseases of childhood.<\/jats:p>","DOI":"10.1155\/2005\/413758","type":"journal-article","created":{"date-parts":[[2016,3,15]],"date-time":"2016-03-15T07:56:39Z","timestamp":1458028599000},"page":"317-320","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Pediatric Interstitial Lung Disease Masquerading as Difficult Asthma: Management Dilemmas for Rare Lung Disease in Children"],"prefix":"10.1155","volume":"12","author":[{"given":"EY","family":"Chan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon D","family":"Dell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,9,3]]},"container-title":["Canadian Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crj\/2005\/413758.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2005\/413758","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T10:08:49Z","timestamp":1722334129000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2005\/413758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["10.1155\/2005\/413758"],"URL":"https:\/\/doi.org\/10.1155\/2005\/413758","archive":["Portico"],"relation":{},"ISSN":["1198-2241","1916-7245"],"issn-type":[{"type":"print","value":"1198-2241"},{"type":"electronic","value":"1916-7245"}],"subject":[],"published":{"date-parts":[[2005,1]]},"assertion":[{"value":"2005-09-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}