{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:54:19Z","timestamp":1761580459179,"version":"3.41.2"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,12,20]],"date-time":"2006-12-20T00:00:00Z","timestamp":1166572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Biomedical Imaging"],"published-print":{"date-parts":[[2007,1]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. To provide PET\/CT image fusion with an improved PET resolution and better contrast ratios than standard reconstructions. <jats:italic>Method<\/jats:italic>. Using a super\u2010resolution algorithm, several PET acquisitions were combined to\nimprove the resolution. In addition, functional PET data was smoothed with a hybrid\ncomputed tomography algorithm (HCT), in which anatomical edge information taken from\nthe CT was employed to retain sharper edges. The combined HCT and super\u2010resolution\ntechnique were evaluated in phantom and patient studies using a clinical PET scanner.\n<jats:italic>Results<\/jats:italic>. In the phantom studies, 3 mm<jats:sub>\u2009<\/jats:sub><jats:sup>18<\/jats:sup>F\u2010FDG sources were resolved. PET contrast ratios\nimproved (average: 54<jats:italic>%<\/jats:italic>, range: 45<jats:italic>%<\/jats:italic>\u201369<jats:italic>%<\/jats:italic>) relative to the standard reconstructions. In the\npatient study, target\u2010to\u2010background ratios also improved (average: 34<jats:italic>%<\/jats:italic>, range: 17<jats:italic>%<\/jats:italic>\u201347<jats:italic>%<\/jats:italic>).\nGiven corresponding anatomical borders, sharper edges were depicted.\n<jats:italic>Conclusion<\/jats:italic>. A new method incorporating super\u2010resolution and HCT for \nfusing PET and CT images has been developed and shown to provide higher\u2010resolution metabolic images.<\/jats:p>","DOI":"10.1155\/2007\/46846","type":"journal-article","created":{"date-parts":[[2006,12,27]],"date-time":"2006-12-27T08:08:20Z","timestamp":1167206900000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Improved Image Fusion in PET\/CT Using Hybrid Image Reconstruction and Super\u2010Resolution"],"prefix":"10.1155","volume":"2007","author":[{"given":"John A.","family":"Kennedy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ora","family":"Israel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"Frenkel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Bar-Shalom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haim","family":"Azhari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,12,20]]},"reference":[{"key":"e_1_2_1_1_2","first-page":"1S","article-title":"A tabulated summary of the FDG PET literature","volume":"42","author":"Gambhir S. S.","year":"2001","journal-title":"Journal of Nuclear Medicine"},{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-2171(03)90037-0"},{"key":"e_1_2_1_3_2","first-page":"756","article-title":"PET instrumentation and reconstruction algorithms in whole-body applications","volume":"44","author":"Tarantola G.","year":"2003","journal-title":"Journal of Nuclear Medicine"},{"key":"e_1_2_1_4_2","doi-asserted-by":"crossref","unstructured":"TownsendD. W. BeyerT. KinahanP. E.et al. The SMART scanner: a combined PET\/CT tomograph for clinical oncology 2 Proceedings of IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS-MIC \u203298) 1998 Toronto Ontario Canada 1170\u20131174 https:\/\/doi.org\/10.1109\/NSSMIC.1998.774368.","DOI":"10.1109\/NSSMIC.1998.774368"},{"key":"e_1_2_1_5_2","first-page":"1369","article-title":"A combined PET\/CT scanner for clinical oncology","volume":"41","author":"Beyer T.","year":"2000","journal-title":"Journal of Nuclear Medicine"},{"key":"e_1_2_1_6_2","first-page":"1200","article-title":"Clinical performance of PET\/CT in evaluation of cancer: additional value for diagnostic imaging and patient management","volume":"44","author":"Bar-Shalom R.","year":"2003","journal-title":"Journal of Nuclear Medicine"},{"key":"e_1_2_1_7_2","first-page":"1640","article-title":"PET\/CT using \u2009\n                  18F-FDG in suspected lung cancer recurrence: diagnostic value and impact on patient management","volume":"45","author":"Keidar Z.","year":"2004","journal-title":"Journal of Nuclear Medicine"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1006\/jvci.1993.1030"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2005.861705"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1006\/cbmr.1997.1439"},{"key":"e_1_2_1_11_2","unstructured":"KennedyJ. A. AzhariH. FrenkelA.et al. PET\/CT Image Data Fusion in Hybrid Scanners Abstract Society of Nuclear Medicine 52nd Annual Meeting Abstract Book 2005 June; Toronto Canada p. 167P."},{"key":"e_1_2_1_12_2","doi-asserted-by":"crossref","unstructured":"GreenspanH. OzG. KiryatiN. andPeledS. Super-resolution in MRI Proceedings of IEEE International Symposium on Biomedical Imaging (ISBI \u203202) July 2002 Washington DC USA 943\u2013946 https:\/\/doi.org\/10.1109\/ISBI.2002.1029417.","DOI":"10.1109\/ISBI.2002.1029417"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0730-725X(02)00511-8"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1109\/TIP.2004.834669"},{"key":"e_1_2_1_15_2","first-page":"1398","article-title":"Performance characteristics of a whole-body PET scanner","volume":"35","author":"DeGrado T. R.","year":"1994","journal-title":"Journal of Nuclear Medicine"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1109\/42.363108"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1109\/42.563660"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-001-0698-9"},{"key":"e_1_2_1_19_2","unstructured":"BeyerT. KinahanP. E. TownsendD. W. andSashinD. The use of x-ray CT for attenuation correction of PET data 4 Proceedings of IEEE Nuclear Science Symposium & Medical Imaging Conference (NSS-MIC \u203295) October-November 1995 San Francisco Calif USA 1573\u20131577 https:\/\/doi.org\/10.1109\/NSSMIC.1994.47476."},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1118\/1.598392"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-002-0796-3"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1109\/TPAMI.1986.4767851"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1109\/42.293921"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1109\/23.173225"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1109\/42.251117"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1109\/83.535846"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1109\/42.870666"}],"container-title":["International Journal of Biomedical Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijbi\/2007\/046846.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijbi\/2007\/046846.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2007\/46846","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T02:54:55Z","timestamp":1720061695000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2007\/46846"}},"subtitle":[],"editor":[{"given":"David","family":"Townsend","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2006,12,20]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,1]]}},"alternative-id":["10.1155\/2007\/46846"],"URL":"https:\/\/doi.org\/10.1155\/2007\/46846","archive":["Portico"],"relation":{},"ISSN":["1687-4188","1687-4196"],"issn-type":[{"type":"print","value":"1687-4188"},{"type":"electronic","value":"1687-4196"}],"subject":[],"published":{"date-parts":[[2006,12,20]]},"assertion":[{"value":"2006-06-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2006-10-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2006-12-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"046846"}}