{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T01:53:03Z","timestamp":1767923583293,"version":"3.49.0"},"reference-count":0,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Canadian Journal of Infectious Diseases and Medical Microbiology"],"published-print":{"date-parts":[[2007,1]]},"abstract":"<jats:p>BACKGROUND: The purpose of the present study was to describe the clinical characteristics and management of community\u2010associated methicillin\u2010resistant <jats:italic>Staphylococcus aureus<\/jats:italic> (CA\u2010MRSA) infections among a cohort of men who have sex with men.<\/jats:p><jats:p>PATIENTS AND METHODS: A retrospective chart review was conducted of patients with culture\u2010proven MRSA at Maple Leaf Medical Clinic (Toronto, Ontario) between November 2004 and December 2005. Cases were identified by individual physicians and by queries in the clinical management system. A standard data collection form was used to record patient demographics, potential risk factors for MRSA and course of illness. When available, antimicrobial sensitivities were recorded. DNA fingerprinting using pulsed\u2010field gel electrophoresis, and genetic analysis for SCC<jats:italic>mec<\/jats:italic> typing and detection of the Panton\u2010Valentine leukocidin cytotoxin were performed on six available isolates.<\/jats:p><jats:p>RESULTS: Seventeen patients with MRSA infection were identified, 12 (71%) of whom were HIV\u2010positive. The most common clinical presentation was abscess (35%), followed by furuncle (17%), folliculitis (17%), cellulitis (17%) and sinusitis (12%). The majority of MRSA isolates were resistant to ciprofloxacin (92%) and levofloxacin (77%). All isolates were susceptible to trimethoprim\u2010sulfamethoxazole, rifampin, linezolid, gentamicin and clindamycin, while the majority were susceptible to tetracycline (80%). All six isolates tested were SCC<jats:italic>mec<\/jats:italic> type IVa\u2010positive and Panton\u2010Valentine leukocidin\u2010positive, and had fingerprint patterns consistent with the CMRSA\u201010 (USA300) clone.<\/jats:p><jats:p>CONCLUSION: The present study describes the clinical presentation and management of CA\u2010MRSA infections occurring in Toronto among men who have sex with men. The infections appear to have been caused by CMRSA\u201010, which has caused the majority of CA\u2010MRSA outbreaks elsewhere.<\/jats:p>","DOI":"10.1155\/2007\/592684","type":"journal-article","created":{"date-parts":[[2016,3,15]],"date-time":"2016-03-15T07:59:57Z","timestamp":1458028797000},"page":"257-261","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Community\u2010Associated Methicillin\u2010Resistant <i>Staphylococcus aureus<\/i> Infections in Men Who Have Sex With Men: A Case Series"],"prefix":"10.1155","volume":"18","author":[{"given":"R","family":"Sztramko","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Katz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Antoniou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MR","family":"Mulvey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Brunetta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Crouzat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Kovacs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Merkley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Tilley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona R","family":"Loutfy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1]]},"container-title":["Canadian Journal of Infectious Diseases and Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjidmm\/2007\/592684.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2007\/592684","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T00:08:16Z","timestamp":1723075696000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2007\/592684"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,1]]}},"alternative-id":["10.1155\/2007\/592684"],"URL":"https:\/\/doi.org\/10.1155\/2007\/592684","archive":["Portico"],"relation":{},"ISSN":["1712-9532","1918-1493"],"issn-type":[{"value":"1712-9532","type":"print"},{"value":"1918-1493","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,1]]},"assertion":[{"value":"2007-01-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}