{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T12:38:20Z","timestamp":1774355900898,"version":"3.50.1"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,7,8]],"date-time":"2008-07-08T00:00:00Z","timestamp":1215475200000},"content-version":"vor","delay-in-days":189,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003006","name":"Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003006","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advances in Bioinformatics"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:p>The Web\u2010based software tool Genevestigator provides powerful tools for biologists to explore gene\nexpression across a wide variety of biological contexts. Its first releases, however, were limited by the scaling\nability of the system architecture, multiorganism data storage and analysis capability, and availability of\ncomputationally intensive analysis methods. Genevestigator V3 is a novel meta\u2010analysis system resulting\nfrom new algorithmic and software development using a client\/server architecture, large\u2010scale manual\ncuration and quality control of microarray data for several organisms, and curation of pathway data for mouse\nand Arabidopsis. In addition to improved querying features, Genevestigator V3 provides new tools to analyze\nthe expression of genes in many different contexts, to identify biomarker genes, to cluster genes into\nexpression modules, and to model expression responses in the context of metabolic and regulatory networks.\nBeing a reference expression database with user\u2010friendly tools, Genevestigator V3 facilitates discovery\nresearch and hypothesis validation.<\/jats:p>","DOI":"10.1155\/2008\/420747","type":"journal-article","created":{"date-parts":[[2008,7,9]],"date-time":"2008-07-09T07:39:14Z","timestamp":1215589154000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1521,"title":["Genevestigator V3: A Reference Expression Database for   the Meta\u2010Analysis of Transcriptomes"],"prefix":"10.1155","volume":"2008","author":[{"given":"Tomas","family":"Hruz","sequence":"first","affiliation":[]},{"given":"Oliver","family":"Laule","sequence":"additional","affiliation":[]},{"given":"Gabor","family":"Szabo","sequence":"additional","affiliation":[]},{"given":"Frans","family":"Wessendorp","sequence":"additional","affiliation":[]},{"given":"Stefan","family":"Bleuler","sequence":"additional","affiliation":[]},{"given":"Lukas","family":"Oertle","sequence":"additional","affiliation":[]},{"given":"Peter","family":"Widmayer","sequence":"additional","affiliation":[]},{"given":"Wilhelm","family":"Gruissem","sequence":"additional","affiliation":[]},{"given":"Philip","family":"Zimmermann","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2008,7,8]]},"reference":[{"key":"e_1_2_7_1_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkg091"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gki022"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nurx.2006.05.005"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2004-5-10-r80"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1104\/pp.104.046367"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-7-311"},{"key":"e_1_2_7_7_2","doi-asserted-by":"crossref","unstructured":"HruzT. tomas.hruz@inf.ethz.ch GruissemW. Hirsch-HoffmannM. andZimmermannP. Reducing Java Internet project risks: a case study of public measurement of client component functionality in the user community Proceedings of the 4th International Conference on Principles and Practices of Programming in Java (PPPJ \u203206) August-September 2006 Mannheim Germany 199\u2013202 https:\/\/doi.org\/10.1145\/1168054.1168083.","DOI":"10.1145\/1168054.1168083"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.25.14863"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btl060"}],"container-title":["Advances in Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/2008\/420747.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2008\/420747.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2008\/420747","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T13:46:21Z","timestamp":1719841581000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2008\/420747"}},"subtitle":[],"editor":[{"given":"Yves","family":"Van de Peer","sequence":"additional","affiliation":[]}],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["10.1155\/2008\/420747"],"URL":"https:\/\/doi.org\/10.1155\/2008\/420747","archive":["Portico"],"relation":{},"ISSN":["1687-8027","1687-8035"],"issn-type":[{"value":"1687-8027","type":"print"},{"value":"1687-8035","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,1]]},"assertion":[{"value":"2008-04-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-05-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-07-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"420747"}}