{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T23:20:26Z","timestamp":1778109626988,"version":"3.51.4"},"reference-count":38,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infectious Diseases in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2008]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Panton-Valentine leukocidin (PVL-)producing<jats:italic>Staphylococcus aureus<\/jats:italic>is emerging as a serious problem worldwide. There has been an increase in the incidence of necrotizing lung infections in otherwise healthy young people with a very high mortality associated with these strains. Sporadic severe infectious complications after incision of Bartholin's abcesses have been described but involvement of<jats:italic>S. aureus<\/jats:italic>is rare.<jats:italic>Case report<\/jats:italic>. We present a 23-year-old apparently healthy female patient without any typical predisposing findings who developed severe sepsis with necrotizing pneumonia and multiple abscesses following incision of a Bartholin's abscess. Methicillin-sensitive<jats:italic>S. aureus<\/jats:italic>harbouring Panton-Valentine leucocidin genes were cultured from the abscess fluid, multiple blood cultures and a postoperative wound swab. Aggressive antibiotic therapy with flucloxacillin, rifampicin and clindamycin, drainage and intensive supportive care lead finally to recovery.<jats:italic>Conclusions<\/jats:italic>.<jats:italic>S. aureus<\/jats:italic>, in particular PVL-positive strains, should be considered when a young, immunocompetent person develops a fulminant necrotizing pneumonia. Minor infections\u2014such as Bartholin's abscess\u2014can precede this life-threating syndrome. Bactericidal antistaphylococcal antibiotics are recommended for treatment, and surgical procedures may become necessary.<\/jats:p>","DOI":"10.1155\/2008\/491401","type":"journal-article","created":{"date-parts":[[2008,7,30]],"date-time":"2008-07-30T08:40:03Z","timestamp":1217407203000},"page":"1-5","source":"Crossref","is-referenced-by-count":12,"title":["Necrotizing Pneumonia Caused by Panton-Valentine Leucocidin-Producing<i>Staphylococcus aureus<\/i>Originating from a Bartholin's Abscess"],"prefix":"10.1155","volume":"2008","author":[{"given":"N.","family":"Jung","sequence":"first","affiliation":[{"name":"Department I of Internal Medicine, University of Cologne, 50935 Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Lehmann","sequence":"additional","affiliation":[{"name":"Department I of Internal Medicine, University of Cologne, 50935 Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Hellmann","sequence":"additional","affiliation":[{"name":"Department I of Internal Medicine, University of Cologne, 50935 Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Seifert","sequence":"additional","affiliation":[{"name":"Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, 50935 Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. 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