{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T16:30:01Z","timestamp":1792427401107,"version":"4.5.0"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,3,18]],"date-time":"2008-03-18T00:00:00Z","timestamp":1205798400000},"content-version":"vor","delay-in-days":77,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mediators of Inflammation"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:p>The present study is performed to investigate the inhibitory effects of Radix Adenophorae extract (RAE) on ovalbumin\u2010induced asthma murine model. To study the anti\u2010inflammatory and antiasthmatic effects of RAE, we examined the development of pulmonary eosinophilic inflammation and inhibitory effects of T cells in murine by RAE and cyclosporine A (CsA). We examined determination of airway hyperresponsiveness, flow cytometric analysis (FACS), enzyme\u2010linked immunosorbent assay (ELISA), quantitative real time (PCR),  hematoxylin\u2010eosin staining, and Masson trichrome staining in lung tissue, lung weight, total cells, and eosinophil numbers in lung tissue. We demonstrated how RAE suppressed development on inflammation and decreased airway damage.<\/jats:p>","DOI":"10.1155\/2008\/781425","type":"journal-article","created":{"date-parts":[[2008,3,19]],"date-time":"2008-03-19T08:20:38Z","timestamp":1205914838000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Effects of Radix Adenophorae and Cyclosporine  A on an OVA\u2010Induced Murine Model of Asthma by Suppressing to T Cells Activity, Eosinophilia, and  Bronchial Hyperresponsiveness"],"prefix":"10.1155","volume":"2008","author":[{"given":"Seong-Soo","family":"Roh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung-Hyung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Cheol","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Bae","family":"Seo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,3,18]]},"reference":[{"key":"e_1_2_4_1_2","volume-title":"Collection of Illustrative Plates for Identification and Application on Clinical Traditional\nChinese Drug","author":"Jun Z. 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