{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T01:10:29Z","timestamp":1773277829906,"version":"3.50.1"},"reference-count":7,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,7,20]],"date-time":"2008-07-20T00:00:00Z","timestamp":1216512000000},"content-version":"vor","delay-in-days":201,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["1-R01-GM072022"],"award-info":[{"award-number":["1-R01-GM072022"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["RUB1-1643-ST-06"],"award-info":[{"award-number":["RUB1-1643-ST-06"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["1-R01-GM072022"],"award-info":[{"award-number":["1-R01-GM072022"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["RUB1-1643-ST-06"],"award-info":[{"award-number":["RUB1-1643-ST-06"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Electrical and Computer Engineering"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:p>We present investigation of gene expression profiles by means of singular spectrum analysis (SSA). The biological\nproblem under investigation is the decomposition of <jats:italic>bicoid<\/jats:italic> protein profiles of <jats:italic>Drosophila melanogaster<\/jats:italic> into\nthe sum of a signal and noise, where the former consists of an exponential\u2010in\u2010distance pattern and is close to constant\nnonspecific component, or \u201cbackground.\u201d The signal processing problems addressed are (i) trend extraction\nfrom a noisy signal, (ii) batch processing of similar data, and (iii) analytical approximation of the signal components\nby the sum of exponential and constant\u2010like functions. The proposed methods are evaluated on the given 17 series.<\/jats:p>","DOI":"10.1155\/2008\/825758","type":"journal-article","created":{"date-parts":[[2008,7,22]],"date-time":"2008-07-22T12:45:27Z","timestamp":1216730727000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Singular Spectrum Analysis of Gene Expression Profiles of Early <i>Drosophila embryo<\/i>: Exponential\u2010in\u2010Distance Patterns"],"prefix":"10.1155","volume":"2008","author":[{"given":"T.","family":"Alexandrov","sequence":"first","affiliation":[]},{"given":"N.","family":"Golyandina","sequence":"additional","affiliation":[]},{"given":"A.","family":"Spirov","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2008,7,20]]},"reference":[{"key":"e_1_2_6_1_2","doi-asserted-by":"publisher","DOI":"10.1201\/9781420035841"},{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.20940"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/415798a"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00427-005-0472-2"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bth222"},{"key":"e_1_2_6_6_2","unstructured":"AlexandrovT. A method of trend extraction using singular spectrum analysis preprint 2008 http:\/\/arxiv.org\/abs\/0804.3367."},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1109\/29.32276"}],"container-title":["Journal of Electrical and Computer Engineering"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jece\/2008\/825758.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jece\/2008\/825758.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2008\/825758","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T13:27:28Z","timestamp":1719581248000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2008\/825758"}},"subtitle":[],"editor":[{"given":"Andreas","family":"Jakobsson","sequence":"additional","affiliation":[]}],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["10.1155\/2008\/825758"],"URL":"https:\/\/doi.org\/10.1155\/2008\/825758","archive":["Portico"],"relation":{},"ISSN":["2090-0147","2090-0155"],"issn-type":[{"value":"2090-0147","type":"print"},{"value":"2090-0155","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,1]]},"assertion":[{"value":"2008-05-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-06-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-07-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"825758"}}