{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:44:24Z","timestamp":1788871464786,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,6,23]],"date-time":"2008-06-23T00:00:00Z","timestamp":1214179200000},"content-version":"vor","delay-in-days":174,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Polish Scientific Committee","award":["2P05B07727"],"award-info":[{"award-number":["2P05B07727"]}]},{"name":"Polish Scientific Committee","award":["503-1019-1"],"award-info":[{"award-number":["503-1019-1"]}]},{"DOI":"10.13039\/501100005888","name":"Medical University of Lodz","doi-asserted-by":"crossref","award":["2P05B07727"],"award-info":[{"award-number":["2P05B07727"]}],"id":[{"id":"10.13039\/501100005888","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005888","name":"Medical University of Lodz","doi-asserted-by":"crossref","award":["503-1019-1"],"award-info":[{"award-number":["503-1019-1"]}],"id":[{"id":"10.13039\/501100005888","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005888","name":"Medical University of Lodz","doi-asserted-by":"crossref","award":["2P05B07727"],"award-info":[{"award-number":["2P05B07727"]}],"id":[{"id":"10.13039\/501100005888","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005888","name":"Medical University of Lodz","doi-asserted-by":"crossref","award":["503-1019-1"],"award-info":[{"award-number":["503-1019-1"]}],"id":[{"id":"10.13039\/501100005888","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mediators of Inflammation"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:p>\n                    As most studies on pemphigus vulgaris (PV) pathogenesis concern its active stage, we aimed to evaluate the serum concentration of TNF\u2010\n                    <jats:italic>\u03b1<\/jats:italic>\n                    , IL\u20101, and IL\u20106 in PV patients in clinical remission. The study group consisted of sera from 19 PV patients in active stage and from 24 patients in clinical remission. 19 sera taken from healthy subjects served as the controls. Serum IL\u20106 concentrations in PV active and PV remission group were significantly higher when compared to the controls (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; .05). In patients in active stage of PV, a significant correlation between serum IL\u20101 and IL\u20106 concentrations was found (\n                    <jats:italic>r<\/jats:italic>\n                    <jats:sub>\n                      <jats:italic>P<\/jats:italic>\n                    <\/jats:sub>\n                    = 0.46;\n                    <jats:italic>P<\/jats:italic>\n                    &lt; .05).  We also found a negative correlation between TNF\u2010\n                    <jats:italic>\u03b1<\/jats:italic>\n                    level and\n                    <jats:italic>pemphigus<\/jats:italic>\n                    antibodies titer in the patients from the remission group (\n                    <jats:italic>r<\/jats:italic>\n                    <jats:sub>\n                      <jats:italic>S<\/jats:italic>\n                    <\/jats:sub>\n                    = \u22120.47303;\n                    <jats:italic>P<\/jats:italic>\n                    &lt; .02). Our data suggest that IL\u20106 and TNF\u2010\n                    <jats:italic>\u03b1<\/jats:italic>\n                    may be involved in maintaining immunological disturbances in remission stage of PV.\n                  <\/jats:p>","DOI":"10.1155\/2008\/875394","type":"journal-article","created":{"date-parts":[[2008,6,24]],"date-time":"2008-06-24T06:45:59Z","timestamp":1214289959000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Serum Concentration of Interleukin\u20106 Is Increased Both in Active and Remission Stages of Pemphigus Vulgaris"],"prefix":"10.1155","volume":"2008","author":[{"given":"Joanna","family":"Narbutt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolanta","family":"Lukamowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaros\u0142aw","family":"Bogaczewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Sysa-Jedrzejowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolanta 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