{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:56:28Z","timestamp":1787752588547,"version":"build-2784847793"},"reference-count":5,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>Pulmonary signs are common in Wegener's granulomatosis (WG). However, an initial presentation including pleural effusion has not been described. We describe a case of WG in which pleural effusion was the first clinical manifestation. A 45-year-old man with dorsal pain presented with pleural thickening and effusion, and a visible nodule on a thoracic scan. A dense chronic inflammatory infiltrate was obtained by pleural biopsy and an open lung biopsy revealed necrotizing granulomatous vasculitis. Serologies were positive for antineutrophil cytoplasmic antibodies and antiproteinase 3 antibodies. A diagnosis of WG was conducted and the patient was started on cyclophosphamide and methylprednisolone as an initial treatment, with a favorable evolution. Although pleural effusion is rarely described in WG, this pathology must be considered in the presence of this clinical manifestation.<\/jats:p>","DOI":"10.1155\/2009\/164395","type":"journal-article","created":{"date-parts":[[2010,2,4]],"date-time":"2010-02-04T10:30:17Z","timestamp":1265279417000},"page":"1-3","source":"Crossref","is-referenced-by-count":9,"title":["Wegener Granulomatosis Revealed by Pleural Effusion"],"prefix":"10.1155","volume":"2009","author":[{"given":"Anne-Claire","family":"Toffart","sequence":"first","affiliation":[{"name":"Clinique de Pneumologie, P\u00f4le M\u00e9decine Aigu\u00eb Communautaire, Centre Hospitalier Universitaire Albert Michallon, 38043 Grenoble cedex 09, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Arbib","sequence":"additional","affiliation":[{"name":"Clinique de Pneumologie, P\u00f4le M\u00e9decine Aigu\u00eb Communautaire, Centre Hospitalier Universitaire Albert Michallon, 38043 Grenoble cedex 09, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie","family":"Lantuejoul","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Pathologie, Centre Hospitalier Universitaire Albert Michallon, 38000 Grenoble, France"},{"name":"INSERM U 823, Universit\u00e9 Joseph Fourier, 38000 Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Fran\u00e7ois","family":"Roux","sequence":"additional","affiliation":[{"name":"Chirurgie G\u00e9n\u00e9rale et Thoracique, Clinique des C\u00e8dres, 38130 Echirolles, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Bland","sequence":"additional","affiliation":[{"name":"Cabinet M\u00e9dical Anatomie Cytologie Pathologiques Ciapa Bland Muller, 38000 Grenoble, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilbert","family":"Ferretti","sequence":"additional","affiliation":[{"name":"INSERM U 823, Universit\u00e9 Joseph Fourier, 38000 Grenoble, France"},{"name":"Clinique Universitaire de Radiologie et Imagerie M\u00e9dicale, Centre Hospitalier Universitaire Albert Michallon, 38043 Grenoble cedex 09, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samia","family":"Diab","sequence":"additional","affiliation":[{"name":"Clinique de Pneumologie, P\u00f4le M\u00e9decine Aigu\u00eb Communautaire, Centre Hospitalier Universitaire Albert Michallon, 38043 Grenoble cedex 09, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"4","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.327.7406.95"},{"key":"3","first-page":"327S","volume":"130","year":"2006","journal-title":"Chest"},{"issue":"4","key":"1","first-page":"265","volume":"56","year":"2000","journal-title":"Revue de Pneumologie Clinique"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.114.2.500"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.2003.01662.x"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2009\/164395.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2009\/164395.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2009\/164395.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T09:07:33Z","timestamp":1471511253000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crim\/2009\/164395\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":5,"alternative-id":["164395","164395"],"URL":"https:\/\/doi.org\/10.1155\/2009\/164395","relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"value":"1687-9627","type":"print"},{"value":"1687-9635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}