{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T22:36:03Z","timestamp":1790980563586,"version":"4.1.0"},"reference-count":51,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Comparative and Functional Genomics"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>Brucellosis is a prevalent zoonotic disease and is endemic in the Middle East, South America, and other areas of the world. In this study, complete inventories of putative functional ABC systems of five<jats:italic>Brucella<\/jats:italic>species have been compiled and compared. ABC systems of<jats:italic>Brucella melitensis<\/jats:italic>16M,<jats:italic>Brucella abortus<\/jats:italic>9-941,<jats:italic>Brucella canis<\/jats:italic>RM6\/66,<jats:italic>Brucella suis<\/jats:italic>1330, and<jats:italic>Brucella ovis<\/jats:italic>63\/290 were identified and aligned. High numbers of ABC systems, particularly nutrient importers, were found in all<jats:italic>Brucella<\/jats:italic>species. However, differences in the total numbers of ABC systems were identified (<jats:italic>B. melitensis<\/jats:italic>, 79;<jats:italic>B. suis<\/jats:italic>, 72;<jats:italic>B. abortus<\/jats:italic>64;<jats:italic>B. canis<\/jats:italic>, 74;<jats:italic>B. ovis<\/jats:italic>, 59) as well as specific differences in the functional ABC systems of the<jats:italic>Brucella<\/jats:italic>species. Since<jats:italic>B. ovis<\/jats:italic>is not known to cause human brucellosis, functional ABC systems absent in the<jats:italic>B. ovis<\/jats:italic>genome may represent virulence factors in human brucellosis.<\/jats:p>","DOI":"10.1155\/2009\/354649","type":"journal-article","created":{"date-parts":[[2010,2,11]],"date-time":"2010-02-11T10:30:25Z","timestamp":1265884225000},"page":"1-16","source":"Crossref","is-referenced-by-count":22,"title":["ATP-Binding Cassette Systems of<i>Brucella<\/i>"],"prefix":"10.1155","volume":"2009","author":[{"given":"Dominic C.","family":"Jenner","sequence":"first","affiliation":[{"name":"Department of Biomedical Sciences, Defence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elie","family":"Dassa","sequence":"additional","affiliation":[{"name":"D\u00e9partment de Microbiologie, Institut Pasteur, 25 rue Dr Roux, 75724 Paris Cedex 15, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian M.","family":"Whatmore","sequence":"additional","affiliation":[{"name":"FAO\/WHO Collaborating Centre for Brucellosis, OIE Brucellosis Reference Centre, Veterinary Laboratories Agency, Addlestone, Surrey KT15 3NB, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen S.","family":"Atkins","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, Defence Science and Technology Laboratory, Porton Down, Salisbury, Wiltshire SP4 0JQ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(06)70382-6"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra050570"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.65269-0"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.65356-0"},{"key":"5","year":"1990"},{"issue":"5","key":"6","first-page":"401","volume":"15","year":"2002","journal-title":"Journal of the American Board of Family Practice"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-006-6311-4"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.221575398"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.192319099"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1128\/JB.187.8.2715-2726.2005"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01581-08"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01767-08"},{"issue":"3","key":"13","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1099\/00207713-35-3-292","volume":"35","year":"1985","journal-title":"International Journal of Systematic Bacteriology"},{"issue":"2","key":"14","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0769-2609(87)90199-2","volume":"138","year":"1987","journal-title":"Annales de l'Institut Pasteur. 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