{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:43:44Z","timestamp":1753886624898,"version":"3.41.2"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2009,7,28]],"date-time":"2009-07-28T00:00:00Z","timestamp":1248739200000},"content-version":"vor","delay-in-days":208,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Endocrinology"],"published-print":{"date-parts":[[2009,1]]},"abstract":"<jats:p>Following myomectomy the rate of fertility is restored and\npregnancy may be attempted with a good outcome. In the present\nstudy a 3 month treatment with OCs in a group of women after a\nmyomectomy was evaluated. The drug compliance and side effects,\nthe benefits of OC in order to reduce symptoms, to increase\npost\u2010surgical hemoglobin levels and to avoid an early pregnancy\nafter myomectomy were analyzed. A group of women (<jats:italic>n<\/jats:italic> = 55) each with myoma \u22655\u2009cm was recruited: they presented menorrhagia,\npelvic pain, dyspareunia and dysmenorrhae. After laparotomic\nmyomectomy the women were divided into 3 groups. Group 1: women\n(<jats:italic>n<\/jats:italic> = 16) treated with pill A (15\u2009mcg of\nethynilestradiol + 60\u2009mcg of gestodene); group 2: women\n(<jats:italic>n<\/jats:italic> = 23) treated with pill B (20\u2009mcg of\nethynilestradiol + 100\u2009mcg of levonorgestrel); group 3:\nwomen (<jats:italic>n<\/jats:italic> = 16) treated with a placebo (oral calcium). After three\nmonths from myomectomy and treatment patients in each group\nreported a reduced menorrhagia, dismenorrhea and pelvic pain. \nSerum haemoglobin levels increased in all women (<jats:italic>P<\/jats:italic> &lt; .05). No pregnancy occurred in any group and the\ncompliance was good. A post surgery treatment by using oral\ncontraceptives guarentees pregnancy prevention, associated with\nreduction of pain, and improvement of haematologic conditions.<\/jats:p>","DOI":"10.1155\/2009\/476897","type":"journal-article","created":{"date-parts":[[2009,7,28]],"date-time":"2009-07-28T15:02:32Z","timestamp":1248793352000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Oral Contraceptives after Myomectomy: A Short Term Trial"],"prefix":"10.1155","volume":"2009","author":[{"given":"Stefano","family":"Luisi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Ciani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Gabbanini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofia","family":"Sollazzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michela","family":"Torricelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Calonaci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felice","family":"Petraglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,7,28]]},"reference":[{"key":"e_1_2_5_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(98)00208-8"},{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.293.6543.359"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-198812000-00008"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00534-6"},{"key":"e_1_2_5_5_2","first-page":"119","article-title":"Determinants of uterine fibroids","volume":"5","author":"Romieu I.","year":"1991","journal-title":"Post Marketing Surveillance"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200004000-00005"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-3552(98)80060-6"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/1071-5576(95)00021-6"},{"key":"e_1_2_5_9_2","first-page":"56","article-title":"Growth of leiomyomata with estrogen\u2014progestogen therapy","volume":"6","author":"John A. 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