{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T19:22:24Z","timestamp":1790018544055,"version":"4.0.1"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Oncology"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p><jats:italic>Objectives<\/jats:italic>. Estimate and compare the proportion of cancer patients with cachexia using different definitions from available clinical data.<jats:italic>Methods<\/jats:italic>. Electronic medical records were examined to estimate the proportion of cancer patients with cachexia using 4 definitions: (1) ICD-9 diagnostic code of 799.4 (cachexia), (2) ICD-9 diagnosis of cachexia, anorexia, abnormal weight loss, or feeding difficulties, (3) prescription for megestrol acetate, oxandrolone, somatropin, or dronabinol, and (4) 5% weight loss. Patients with cancer of the stomach, pancreas, lung, colon\/rectum, head\/neck, esophagus, prostate, breast, or liver diagnosed between 1999 and 2004 were followed for cachexia.<jats:italic>Results<\/jats:italic>. Of 8541 cancer patients (60% men and 55% Caucasian), cachexia was observed in 2.4% of patients using the cachexia diagnostic code, 5.5% expanded diagnoses, 6.4% prescription medication definition, and 14.7% with 5% weight loss.<jats:italic>Conclusions<\/jats:italic>. The proportion of patients with cachexia varied considerably depending upon the definition employed, indicating that a standard operational definition is needed.<\/jats:p>","DOI":"10.1155\/2009\/693458","type":"journal-article","created":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T09:38:38Z","timestamp":1246441118000},"page":"1-7","source":"Crossref","is-referenced-by-count":84,"title":["Estimation of Cachexia among Cancer Patients Based on Four Definitions"],"prefix":"10.1155","volume":"2009","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2100-277X","authenticated-orcid":true,"given":"Kathleen M.","family":"Fox","sequence":"first","affiliation":[{"name":"Strategic Healthcare Solutions, LLC, P.O. 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