{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T07:27:25Z","timestamp":1791012445637,"version":"4.1.0"},"reference-count":0,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000081","name":"Danone Institute of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000081","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Journal of Gastroenterology"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>BACKGROUND: The genetics of intestinal lactase divide the world\u2019s population into two phenotypes: the ability (a dominant trait) or inability (a recessive trait) to digest lactose. A prebiotic effect of lactose may impact the colonic flora of these phenotypes differently.<\/jats:p><jats:p>OBJECTIVE: To detect and evaluate the effects of lactose on subjects divided according to their ability to digest lactose.<\/jats:p><jats:p>METHODS: A total of 57 healthy maldigesters (n=30) and digesters (n=27) completed diet questionnaires, genetic and breath hydrogen testing, and quantitative stool analysis for species of bacteria. Log<jats:sub>10<\/jats:sub>transformation of bacterial counts was compared with lactose intake in both groups using multiple regression analysis.<\/jats:p><jats:p>RESULTS: There was a significant relationship between genetic and breath hydrogen tests. Daily lactose intake was marginally lower in lactose maldigesters (median [interquartile range] 12.2 g [31 g] versus 15 g [29.6 g], respectively). There was no relationship between lactose intake and breath hydrogen tests in either group. There were no differences in bacterial counts between the two groups, nor was there a relationship between bacterial counts and lactose intake in either group.<\/jats:p><jats:p>CONCLUSION: The differential bacterial effects of lactose were not quantitatively detected in stool samples taken in the present study.<\/jats:p>","DOI":"10.1155\/2009\/693794","type":"journal-article","created":{"date-parts":[[2016,3,15]],"date-time":"2016-03-15T04:02:55Z","timestamp":1458014575000},"page":"753-759","source":"Crossref","is-referenced-by-count":6,"title":["Lack of Effect of Lactose Digestion Status on Baseline Fecal Microflora"],"prefix":"10.1155","volume":"23","author":[{"given":"Andrew","family":"Szilagyi","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Department of Medicine, Sir Mortimer B Davis Jewish General Hospital, McGill School of Medicine, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Shrier","sequence":"additional","affiliation":[{"name":"Centre for Clinical Epidemiology and Community Studies, Lady Davis Institute for Medical Research, Sir Mortimer B Davis Jewish General Hospital, McGill University, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Chong","sequence":"additional","affiliation":[{"name":"Division of Laboratory Genetic Testing, Department of Biochemistry, Sir Mortimer B Davis Jewish General Hospital, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Sung","family":"Je","sequence":"additional","affiliation":[{"name":"Department of Food Science, Macdonald Campus, McGill University, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunghoon","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Food Science, Macdonald Campus, McGill University, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debra","family":"Heilpern","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Medicine, Sir Mortimer B Davis Jewish General Hospital, McGill School of Medicine, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Lalonde","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Medicine, Sir Mortimer B Davis Jewish General Hospital, McGill School of Medicine, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis-Francois","family":"Cote","sequence":"additional","affiliation":[{"name":"Department of Dietetics, Sir Mortimer B Davis Jewish General Hospital, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Food Science, Macdonald Campus, McGill University, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","container-title":["Canadian Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2009\/693794.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2009\/693794.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,23]],"date-time":"2016-08-23T09:56:28Z","timestamp":1471946188000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/cjgh\/2009\/693794\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":0,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2009]]}},"alternative-id":["693794"],"URL":"https:\/\/doi.org\/10.1155\/2009\/693794","relation":{},"ISSN":["0835-7900"],"issn-type":[{"value":"0835-7900","type":"print"}],"subject":[],"published":{"date-parts":[[2009]]}}}