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NF1 patients are predisposed to a 5-fold increased incidence of high-grade astrocytomas, which are usually located in supratentorial regions of the brain. We present an NF1 patient who developed a high-grade astrocytoma in the posterior fossa and discuss possible pathophysiological mechanisms.<\/jats:p>","DOI":"10.1155\/2009\/757898","type":"journal-article","created":{"date-parts":[[2009,12,16]],"date-time":"2009-12-16T10:30:21Z","timestamp":1260959421000},"page":"1-4","source":"Crossref","is-referenced-by-count":15,"title":["Glioblastoma Multiforme in the Posterior Cranial Fossa in a Patient with Neurofibromatosis Type I"],"prefix":"10.1155","volume":"2009","author":[{"given":"Marike L. 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