{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T13:36:39Z","timestamp":1762004199419},"reference-count":10,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>We present an exceptional case of a giant urachal tumor, consisting of both villous adenoma and mucinous adenocarcinoma of the urachus. The tumor was incidentally discovered during investigations for renal failure. Initial transurethral biopsies showed only a villous adenoma of the urachus. Although the biopsies showed no malignancy, a radical cystoprostatectomy and broad excision of the urachus and umbilicus were performed. At the same time, a bilateral nephroureterectomy was performed because of reflux-nephropathy and renal failure. The indication for surgery was based on the typical imaging aspects, raising the suspicion of an underlying urachal adenocarcinoma (size and location). Indeed, at final histopathology a concomitant well-differentiated adenocarcinoma of the urachus confined to the urachal mucosa was found. The patient remained free of disease for 50 months of follow-up. Only three previous cases of urachal adenocarcinoma associated with villous adenoma have been described.<\/jats:p>","DOI":"10.1155\/2009\/818646","type":"journal-article","created":{"date-parts":[[2010,2,18]],"date-time":"2010-02-18T04:23:45Z","timestamp":1266467025000},"page":"1-4","source":"Crossref","is-referenced-by-count":4,"title":["A Giant Mucinous Adenocarcinoma Arising within a Villous Adenoma of the Urachus: Case Report and Review of the Literature"],"prefix":"10.1155","volume":"2009","author":[{"given":"Steven","family":"Joniau","sequence":"first","affiliation":[{"name":"Department of Urology, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evelyne","family":"Lerut","sequence":"additional","affiliation":[{"name":"Department of Pathology, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hein","family":"Van Poppel","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"issue":"1","key":"1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0022-5347(17)50167-6","volume":"131","year":"1984","journal-title":"Journal of Urology"},{"key":"2","first-page":"68","volume":"119","year":"1955","journal-title":"Journal of Urology"},{"issue":"2","key":"3","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0022-5347(17)34950-9","volume":"151","year":"1994","journal-title":"Journal of Urology"},{"issue":"6","key":"4","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1016\/S0022-5347(17)46056-3","volume":"135","year":"1986","journal-title":"Journal of Urology"},{"issue":"6","key":"5","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1093\/ajcp\/79.6.728","volume":"79","year":"1983","journal-title":"American Journal of Clinical Pathology"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.46.5.450"},{"issue":"3","key":"7","first-page":"266","volume":"18","year":"1995","journal-title":"Chang Gung Medical Journal"},{"issue":"2","key":"8","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0022-5347(17)57461-3","volume":"119","year":"1978","journal-title":"Journal of Urology"},{"key":"9","first-page":"173","volume":"2","year":"1994","journal-title":"Journal of Urologic Pathology"},{"issue":"6","key":"10","first-page":"465","volume":"56","year":"2003","journal-title":"Journal of Clinical Pathology"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2009\/818646.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2009\/818646.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2009\/818646.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,25]],"date-time":"2019-05-25T21:20:43Z","timestamp":1558819243000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crim\/2009\/818646\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":10,"alternative-id":["818646","818646"],"URL":"https:\/\/doi.org\/10.1155\/2009\/818646","relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"value":"1687-9627","type":"print"},{"value":"1687-9635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}