{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T19:42:52Z","timestamp":1783539772895,"version":"3.55.0"},"reference-count":0,"publisher":"Hindawi Limited","issue":"12","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Journal of Gastroenterology"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>Two cases of fulminant pulmonary legionellosis, complicated by prolonged intensive care unit stays and acute respiratory distress syndrome, and who were recently treated with infliximab for Crohn\u2019s disease, are described. A review of the literature revealed three additional cases in patients with inflammatory bowel disease, and a total of 22 cases of<jats:italic>Legionella pneumophila<\/jats:italic>pneumonia in the context of treatment with antitumour necrosis (TNF)-alpha medications. The median age of the patients was 49 years, and men and women were affected equally. The case fatality rate was 14% (three of 22). Early recognition and treatment of this anti-TNF-alpha-related complication would likely result in reduced mortality and morbidity. Physicians prescribing anti-TNF-alpha drugs should be aware of this association.<\/jats:p>","DOI":"10.1155\/2009\/836938","type":"journal-article","created":{"date-parts":[[2016,3,15]],"date-time":"2016-03-15T04:05:53Z","timestamp":1458014753000},"page":"829-833","source":"Crossref","is-referenced-by-count":17,"title":["Fulminant Legionellosis in Two Patients Treated with Infliximab for Crohn\u2019s Disease: Case Series and Literature Review"],"prefix":"10.1155","volume":"23","author":[{"given":"Adam","family":"Hofmann","sequence":"first","affiliation":[{"name":"Department of General Internal Medicine, McGill University Faculty of Medicine, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanick","family":"Beaulieu","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Critical Care, H\u00f4pital Sacr\u00e9-C\u0153ur, Montreal University, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Bernard","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Critical Care, H\u00f4pital Sacr\u00e9-C\u0153ur, Montreal University, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Rico","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Critical Care, H\u00f4pital Sacr\u00e9-C\u0153ur, Montreal University, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","container-title":["Canadian Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2009\/836938.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2009\/836938.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,23]],"date-time":"2016-08-23T11:37:58Z","timestamp":1471952278000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/cjgh\/2009\/836938\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2009]]}},"alternative-id":["836938"],"URL":"https:\/\/doi.org\/10.1155\/2009\/836938","relation":{},"ISSN":["0835-7900"],"issn-type":[{"value":"0835-7900","type":"print"}],"subject":[],"published":{"date-parts":[[2009]]}}}