{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T15:22:29Z","timestamp":1770996149319,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["384330"],"award-info":[{"award-number":["384330"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001779","name":"Monash University","doi-asserted-by":"publisher","award":["384330"],"award-info":[{"award-number":["384330"]}],"id":[{"id":"10.13039\/501100001779","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004342","name":"Wyeth","doi-asserted-by":"publisher","award":["384330"],"award-info":[{"award-number":["384330"]}],"id":[{"id":"10.13039\/100004342","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Sanofi-Aventis Australia","award":["384330"],"award-info":[{"award-number":["384330"]}]},{"name":"Abbott Australasia","award":["384330"],"award-info":[{"award-number":["384330"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Rheumatology"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p><jats:italic>Aims<\/jats:italic>. To describe the baseline characteristics of an Australian population-based cohort of rheumatoid arthritis (RA) patients commencing biological therapy.<jats:italic>Methods<\/jats:italic>. Descriptive analysis from the Australian Rheumatology Association Database (ARAD).<jats:italic>Results<\/jats:italic>. Up to October 2006, there were 681 RA patients taking biologics enrolled in ARAD. Baseline data were available for 624 (72% female, mean (SD) age 57.0 (12.5) years). Of these, 59.5% reported at least one comorbid condition, most commonly hypertension (35.7%) and osteoporosis (30.4%); 61 (9.8%) had a history of malignancy (35 nonmelanoma skin, 5 breast, 4 bowel, 5 cervix, 3 melanoma, 3 prostate and 1 each of lip, lung, myeloma, testis, uterus, vagina). Self-reported infections within the previous 6 months were common (71.5%).<jats:italic>Conclusions<\/jats:italic>. History of comorbidities, including recent infections, is common among Australian RA patients commencing biologics, and 10% have a history of malignancy. This may impact future evaluations of health outcomes among this population, including attribution of adverse events of biologic therapy.<\/jats:p>","DOI":"10.1155\/2009\/861481","type":"journal-article","created":{"date-parts":[[2009,9,2]],"date-time":"2009-09-02T07:28:32Z","timestamp":1251876512000},"page":"1-8","source":"Crossref","is-referenced-by-count":18,"title":["Baseline Comorbidities in a Population-Based Cohort of Rheumatoid Arthritis Patients Receiving Biological Therapy: Data from the Australian Rheumatology Association Database"],"prefix":"10.1155","volume":"2009","author":[{"given":"Andrew M.","family":"Briggs","sequence":"first","affiliation":[{"name":"Monash Department of Clinical Epidemiology, Cabrini Hospital, Malvern, Victoria, Australia"},{"name":"School of Physiotherapy and Curtin Health and Innovation Research Institute, Curtin University of Technology, Perth, WA, 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