{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T10:16:13Z","timestamp":1756894573881},"reference-count":0,"publisher":"Hindawi Limited","issue":"10","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Journal of Gastroenterology"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:p>BACKGROUND: Despite the availability of several methods (invasive and noninvasive) for the diagnosis of<jats:italic>Helicobacter pylori<\/jats:italic>infection, no test is considered to be the \u2018gold standard\u2019. Endoscopy-based tests are regarded as the reference method in most studies.<\/jats:p><jats:p>OBJECTIVE: To evaluate the diagnostic performance of imprint cytology smears of antral biopsies compared with Gram-stained smears, the rapid urease test and culture methods, separately and in combination.<\/jats:p><jats:p>METHODS: Antral biopsies were obtained from consecutive patients undergoing upper gastrointestinal endoscopy at a single centre. The biopsies were examined for the presence of<jats:italic>H pylori<\/jats:italic>by Gram-stained smear, the rapid urease test, culture methods and imprint cytology smear.<\/jats:p><jats:p>RESULTS: A total of 273 biopsies were studied. All tests were positive in 36% of the patients. Of 252 biopsies tested, 73% were positive using the imprint cytology technique. Using Gram-stained smear, the rapid urease test and culture methods individually, the sensitivity and specificity of imprint cytology smears for the detection of<jats:italic>H pylori<\/jats:italic>were found to be 92.7% and 50%; 92.7% and 49%; and 92.4% and 38.5%, respectively. Combining the three microbiological methods resulted in a sensitivity of 92.1%, a specificity of 51.0% and an efficiency of 71.7% for imprint cytology smears.<\/jats:p><jats:p>CONCLUSIONS: Endoscopic examination provides useful clinical information. Imprint gastric cytology can be used as a rapid test to establish the diagnosis of<jats:italic>H pylori<\/jats:italic>infection at the time endoscopy is performed, enabling the endoscopist to start treatment with immediate effect.<\/jats:p>","DOI":"10.1155\/2010\/156310","type":"journal-article","created":{"date-parts":[[2016,3,15]],"date-time":"2016-03-15T07:50:18Z","timestamp":1458028218000},"page":"603-606","source":"Crossref","is-referenced-by-count":4,"title":["Diagnostic Performance of Gastric Imprint Smear for Determination of<i>Helicobacter pylori<\/i>Infection"],"prefix":"10.1155","volume":"24","author":[{"given":"J","family":"Al-Ali","sequence":"first","affiliation":[{"name":"Department of Medicine, Faculty of Medicine, Kuwait University, Jabriya, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Al-Asfar","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Medicine, Kuwait University, Jabriya, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Dhar","sequence":"additional","affiliation":[{"name":"Department of Laboratories (Microbiology Unit), Al-Adan Hospital, Hadiya, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PM","family":"Dhar","sequence":"additional","affiliation":[{"name":"Department of Surgery, Al-Adan Hospital, Hadiya, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Kapila","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kuwait University, Jabriya, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","container-title":["Canadian Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2010\/156310.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2010\/156310.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,23]],"date-time":"2016-08-23T07:04:50Z","timestamp":1471935890000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/cjgh\/2010\/156310\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":0,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2010]]}},"alternative-id":["156310"],"URL":"https:\/\/doi.org\/10.1155\/2010\/156310","relation":{},"ISSN":["0835-7900"],"issn-type":[{"value":"0835-7900","type":"print"}],"subject":[],"published":{"date-parts":[[2010]]}}}