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Cytokines exert their biological activities through the activation and translocation of transcription factors into the nucleus whether they drive the expression of specific cytokine-responsive genes. Signal transducer and activator of transcription (STATs) are transcription factors which play a critical role in mediating signaling downstream of cytokine receptors and are important for shaping the host immune response during<jats:italic>Leishmania<\/jats:italic>infection. Here we discuss the signature cytokines and their associated STATs involved in the host immune response during cutaneous and visceral leishmaniasis.<\/jats:p>","DOI":"10.1155\/2010\/294389","type":"journal-article","created":{"date-parts":[[2010,3,15]],"date-time":"2010-03-15T15:30:12Z","timestamp":1268667012000},"page":"1-6","source":"Crossref","is-referenced-by-count":54,"title":["Cytokines and Their STATs in Cutaneous and Visceral Leishmaniasis"],"prefix":"10.1155","volume":"2010","author":[{"given":"Hannah E.","family":"Cummings","sequence":"first","affiliation":[{"name":"Department of Microbiology, The Ohio State University, 484 West 12th Avenue, Columbus, OH 43210, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashmi","family":"Tuladhar","sequence":"additional","affiliation":[{"name":"Department of Microbiology, The Ohio State University, 484 West 12th Avenue, Columbus, OH 43210, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhay 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