{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T20:37:51Z","timestamp":1780519071515,"version":"3.54.1"},"reference-count":9,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2010,6,6]],"date-time":"2010-06-06T00:00:00Z","timestamp":1275782400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Allergy"],"published-print":{"date-parts":[[2010,6,6]]},"abstract":"<jats:p>Type I hypersensitivity is driven by allergen specific immunoglobulin E (sIgE) and thus sIgE represents a marker for modern allergy diagnosis. Recently, a rapid assay for the detection of sIgE, termed as (Allergy Lateral Flow Assay) ALFA, has been developed. The objective of our study is the evaluation of a scanner-based system for the semiquantitative interpretation of ALFA results. Agreement to Skin Prick Test (SPT, Allergopharma), ALLERG-O-LIQ System (Dr. Fooke), and ImmunoCAP (Phadia) was investigated using 50 sera tested for specific IgE to timothy grass pollen (g6). 35\/50 sera were positive by SPT, ALLERG-O-LIQ, and ImmunoCAP. Excellent agreement was observed between ALFA results and SPT, ImmunoCAP, and ALLERG-O-LIQ. Area under the curve (AUC) values were found at 1.0, and 100% sensitivity and specificity was found versus all other methods. Visual- and scanner-based interpretation of the ALFA results revealed excellent agreement.<\/jats:p>","DOI":"10.1155\/2010\/524084","type":"journal-article","created":{"date-parts":[[2010,6,6]],"date-time":"2010-06-06T14:34:26Z","timestamp":1275834866000},"page":"1-4","source":"Crossref","is-referenced-by-count":7,"title":["Evaluation of a Novel Rapid Test System for the Detection of Allergic Sensitization to Timothy Grass Pollen against Established Laboratory Methods and Skin Prick Test"],"prefix":"10.1155","volume":"2010","author":[{"given":"R.","family":"Lucassen","sequence":"first","affiliation":[{"name":"Dr. Fooke Laboratorien GmbH, Mainstra\u00dfe 85, 41469 Neuss, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Schulte-Pelkum","sequence":"additional","affiliation":[{"name":"Dr. Fooke Laboratorien GmbH, Mainstra\u00dfe 85, 41469 Neuss, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Csuvarszki","sequence":"additional","affiliation":[{"name":"Allergy and Asthma Center Westend, Spandauer Damm 130, 14050 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Kleine-Tebbe","sequence":"additional","affiliation":[{"name":"Allergy and Asthma Center Westend, Spandauer Damm 130, 14050 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Fooke","sequence":"additional","affiliation":[{"name":"Dr. Fooke Laboratorien GmbH, Mainstra\u00dfe 85, 41469 Neuss, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Mahler","sequence":"additional","affiliation":[{"name":"Dr. Fooke Laboratorien GmbH, Mainstra\u00dfe 85, 41469 Neuss, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"issue":"7523","key":"1","first-page":"951","volume":"2","year":"1967","journal-title":"Lancet"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2004.06.046"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1034\/j.1398-9995.2003.00281.x"},{"issue":"3","key":"4","first-page":"223","volume":"18","year":"2008","journal-title":"Journal of Investigational Allergology and Clinical Immunology"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.2008.00827.x"},{"key":"6","first-page":"128","volume":"62","year":"2007","journal-title":"Allergy"},{"issue":"4","key":"7","doi-asserted-by":"crossref","first-page":"129","DOI":"10.5414\/ALP27129","volume":"27","year":"2004","journal-title":"Allergologie"},{"issue":"2","key":"9","first-page":"75","volume":"16","year":"2006","journal-title":"Journal of Investigational Allergology and Clinical Immunology"},{"issue":"6","key":"10","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1067\/mai.2003.1521","volume":"111","year":"2003","journal-title":"Journal of Allergy and Clinical Immunology"}],"container-title":["Journal of Allergy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/2010\/524084.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2010\/524084.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2010\/524084.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T05:19:53Z","timestamp":1607491193000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/ja\/2010\/524084\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6,6]]},"references-count":9,"alternative-id":["524084","524084"],"URL":"https:\/\/doi.org\/10.1155\/2010\/524084","relation":{},"ISSN":["1687-9783","1687-9791"],"issn-type":[{"value":"1687-9783","type":"print"},{"value":"1687-9791","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6,6]]}}}