{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T16:41:59Z","timestamp":1768322519377,"version":"3.49.0"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,8,16]],"date-time":"2010-08-16T00:00:00Z","timestamp":1281916800000},"content-version":"vor","delay-in-days":227,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obstetrics and Gynecology International"],"published-print":{"date-parts":[[2010,1]]},"abstract":"<jats:p>Magnetic resonance\u2010guided focused ultrasound surgery (MRgFUS) is a non\u2010invasive treatment approach for symptomatic uterine fibroids. One imaging characteristic considered in selecting patients who may benefit from MRgFUS of their uterine fibroids is the signal intensity of the fibroid compared with surrounding myometrium on T2\u2010weighted MR images. Previous reports suggest that hyper\u2010intense fibroids are less amenable to MRgFUS compared with iso\u2010 or hypo\u2010intense fibroids. In this case study, we utilized contrast\u2010enhanced dynamic MR imaging to further characterize the vascularity of a hyper\u2010intense fibroid. Based on the results of dynamic T1\u2010weighted contrast\u2010enhanced images, we assumed that the hyper\u2010intense appearance resulted from high fluid content rather than high vascularity and predicted that the fibroid would respond to MRgFUS. The patient underwent the MRgFUS without complication and reported significant decrease in fibroid symptoms at 3 and 12 months post\u2010treatment. This case suggests that pre\u2010treatment dynamic contrast\u2010enhanced imaging used in conjunction with T2\u2010weighted imaging may improve the criteria for selecting uterine fibroids amenable to treatment with MRgFUS, potentially leading to improved patient outcomes.<\/jats:p>","DOI":"10.1155\/2010\/834275","type":"journal-article","created":{"date-parts":[[2010,8,16]],"date-time":"2010-08-16T18:33:41Z","timestamp":1281983621000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Contrast\u2010Enhanced Dynamic MR Imaging of Uterine Fibroids as a Potential Predictor of Patient Eligibility for MR Guided Focused Ultrasound (MRgFUS) Treatment for Symptomatic Uterine Fibroids"],"prefix":"10.1155","volume":"2010","author":[{"given":"Sang-Wook","family":"Yoon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chan","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyoung Ah","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Heum","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,8,16]]},"reference":[{"key":"e_1_2_5_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)45789-4"},{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/94.4.435"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/RMR.0b013e3180337e1f"},{"key":"e_1_2_5_4_2","first-page":"1","article-title":"Management of uterine fibroids: an update of the evidence","author":"Viswanathan M.","year":"2007","journal-title":"Evidence Report\/Technology Assessment"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)03622-9"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2007.03.053"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.4099"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000275283.39475.f6"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2007.00665.x"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-008-1086-7"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2007.04.009"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(01)01702-1"}],"container-title":["Obstetrics and Gynecology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ogi\/2010\/834275.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ogi\/2010\/834275.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2010\/834275","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T16:33:21Z","timestamp":1722875601000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2010\/834275"}},"subtitle":[],"editor":[{"given":"Liselotte","family":"Mettler","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2010,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1]]}},"alternative-id":["10.1155\/2010\/834275"],"URL":"https:\/\/doi.org\/10.1155\/2010\/834275","archive":["Portico"],"relation":{},"ISSN":["1687-9589","1687-9597"],"issn-type":[{"value":"1687-9589","type":"print"},{"value":"1687-9597","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1]]},"assertion":[{"value":"2010-01-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-07-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-08-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"834275"}}