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Since the physical experiment is usually complicated and expensive, research methods based on simulation platforms have obtained extensive attention. We developed a simulation platform named Molecular Optical Simulation Environment (MOSE) to simulate photon transport in both biological tissues and free space for optical imaging based on noncontact measurement. In this platform, Monte Carlo (MC) method and the hybrid radiosity\u2010radiance theorem are used to simulate photon transport in biological tissues and free space, respectively, so both contact and noncontact measurement modes of optical imaging can be simulated properly. In addition, a parallelization strategy for MC method is employed to improve the computational efficiency. In this paper, we study the photon transport problems in both biological tissues and free space using MOSE. The results are compared with Tracepro, simplified spherical harmonics method (<jats:italic>S<\/jats:italic><jats:italic>P<\/jats:italic><jats:sub><jats:italic>n<\/jats:italic><\/jats:sub>), and physical measurement to verify the performance of our study method on both accuracy and efficiency.<\/jats:p>","DOI":"10.1155\/2010\/913434","type":"journal-article","created":{"date-parts":[[2010,4,22]],"date-time":"2010-04-22T15:31:35Z","timestamp":1271950295000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Study on Photon Transport Problem Based on the Platform of Molecular Optical Simulation Environment"],"prefix":"10.1155","volume":"2010","author":[{"given":"Kuan","family":"Peng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinbo","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jimin","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaochao","family":"Qu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nunu","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueli","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Tian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,4,22]]},"reference":[{"key":"e_1_2_7_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1074"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bioeng.4.111901.093336"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1088\/0031\u20109155\/42\/5\/008"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1088\/0031\u20109155\/50\/4\/R01"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1118\/1.598868"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0169\u20102607(95)01640\u2010F"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1364\/OE.15.014086"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1364\/OE.10.000159"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2004.05.021"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1118\/1.595361"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1364\/AO.41.007114"},{"key":"e_1_2_7_12_2","unstructured":"BriesmeisterJ. 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Light transport in tissue Ph.D. dissertation 1988 University of Texas Austin Tex USA."},{"volume-title":"Infrared Physics","year":"2004","author":"Zhang J.","key":"e_1_2_7_19_2"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcp.2006.07.007"},{"key":"e_1_2_7_21_2","doi-asserted-by":"crossref","unstructured":"QinD. ZhaoH. TanikawaY. andGaoF. gaofeng@tju.edu.cn Experimental determination of optical properties in turbid medium by TCSPC technique 6434 Optical Tomography and Spectroscopy of Tissue VII January 2007 Proceedings of SPIE 2-s2.0-34247358636 https:\/\/doi.org\/10.1117\/12.697860.","DOI":"10.1117\/12.697860"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1088\/0031\u20109155\/50\/17\/021"}],"container-title":["International Journal of Biomedical Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijbi\/2010\/913434.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijbi\/2010\/913434.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2010\/913434","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T11:28:36Z","timestamp":1718796516000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2010\/913434"}},"subtitle":[],"editor":[{"given":"Shan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2010,1]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1]]}},"alternative-id":["10.1155\/2010\/913434"],"URL":"https:\/\/doi.org\/10.1155\/2010\/913434","archive":["Portico"],"relation":{},"ISSN":["1687-4188","1687-4196"],"issn-type":[{"type":"print","value":"1687-4188"},{"type":"electronic","value":"1687-4196"}],"subject":[],"published":{"date-parts":[[2010,1]]},"assertion":[{"value":"2009-09-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-02-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-04-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"913434"}}