{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T00:58:40Z","timestamp":1648601920701},"reference-count":35,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Fundo de Incentivo \u00e0 Pesquisa\u2014Hospital de Cl\u00ednicas de Porto Alegre"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical and Developmental Immunology"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Tuberculosis (TB) is a cause of significant morbidity and mortality in patients with AIDS. The goal of our study was to determine predictors of in-hospital mortality in patients with AIDS and disseminated tuberculosis in a middle-income country.<jats:italic>Material and Methods<\/jats:italic>. We conducted a retrospective cohort study in a tertiary care center, for patients with AIDS in southern Brazil. From 1996 to 2008, all patients with the diagnosis of disseminated TB were included.<jats:italic>Results<\/jats:italic>. Eighty patients were included. In-hospital mortality was 35%\u2009\u2009<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mrow><mml:mo>(<\/mml:mo><mml:mrow><mml:mi>N<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>28<\/mml:mn><\/mml:mrow><mml:mo>)<\/mml:mo><\/mml:mrow><\/mml:mrow><\/mml:math>. On multivariate Cox regression analysis, low basal albumin<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mrow><mml:mo>(<\/mml:mo><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>.01<\/mml:mn><\/mml:mrow><mml:mo>)<\/mml:mo><\/mml:mrow><\/mml:mrow><\/mml:math>was associated with death, and fever at admission was related to better survival<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mrow><mml:mo>(<\/mml:mo><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>.01<\/mml:mn><\/mml:mrow><mml:mo>)<\/mml:mo><\/mml:mrow><\/mml:mrow><\/mml:math>.<jats:italic>Conclusion<\/jats:italic>. Albumin levels or fever are independent predictors of survival in patients with HIV and disseminated TB. They can serve as indirect markers of immunodeficiency in patients with disseminated TB and AIDS.<\/jats:p>","DOI":"10.1155\/2011\/120278","type":"journal-article","created":{"date-parts":[[2010,8,4]],"date-time":"2010-08-04T22:19:04Z","timestamp":1280960344000},"page":"1-6","source":"Crossref","is-referenced-by-count":3,"title":["In-Hospital Mortality of Disseminated Tuberculosis in Patients Infected with the Human Immunodeficiency Virus"],"prefix":"10.1155","volume":"2011","author":[{"given":"Rodrigo Pires","family":"dos Santos","sequence":"first","affiliation":[{"name":"Infectious Disease Service, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Universidade Federal do Rio Grande do Sul (UFRGS), 90035-003, Porto Alegre, RS, Brazil"},{"name":"Comiss\u00e3o de Controle de Infec\u00e7\u00e3o, Hospital de Cl\u00ednicas de Porto Alegre (HCPA), 90035-003 Ramiro Barcelos 2350, Porto Alegre, RS, 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