{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T19:34:36Z","timestamp":1774121676060,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Government of Kuwait"},{"name":"Governments of Sweden"},{"name":"Government of the Republic of Korea"},{"DOI":"10.13039\/100004334","name":"Merck","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004334","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Interdisciplinary Perspectives on Infectious Diseases"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>To help understand the potential impact of bacterial coinfection during pandemic influenza periods, we undertook a far-reaching review of the existing literature to gain insights into the interaction of influenza and bacterial pathogens. Reports published between 1950 and 2006 were identified from scientific citation databases using standardized search terms. Study outcomes related to coinfection were subjected to a pooled analysis. Coinfection with influenza and bacterial pathogens occurred more frequently in pandemic compared with seasonal influenza periods. The most common bacterial coinfections with influenza virus were due to<jats:italic>S. pneumoniae<\/jats:italic>,<jats:italic>H. influenzae<\/jats:italic>,<jats:italic>Staphylococcus spp<\/jats:italic>., and<jats:italic>Streptococcus spp<\/jats:italic>. Of these,<jats:italic>S. pneumoniae<\/jats:italic>was the most common cause of bacterial coinfection with influenza and accounted for 40.8% and 16.6% of bacterial coinfections during pandemic and seasonal periods, respectively. These results suggest that bacterial pathogens will play a key role in many countries, as the H1N1(A) influenza pandemic moves forward. Given the role of bacterial coinfections during influenza epidemics and pandemics, the conduct of well-designed field evaluations of public health measures to reduce the burden of these common bacterial pathogens and influenza in at-risk populations is warranted.<\/jats:p>","DOI":"10.1155\/2011\/146376","type":"journal-article","created":{"date-parts":[[2011,5,11]],"date-time":"2011-05-11T19:32:27Z","timestamp":1305142347000},"page":"1-6","source":"Crossref","is-referenced-by-count":20,"title":["Influenza and Bacterial Pathogen Coinfections in the 20th Century"],"prefix":"10.1155","volume":"2011","author":[{"given":"Xuan-Yi","family":"Wang","sequence":"first","affiliation":[{"name":"Center for Public Health and Infectious Disease, Institutes of Biomedical Sciences, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, China"},{"name":"Key Laboratory of Medical Molecular Virology of MoH & MoE, Shanghai Medical College, Fudan University, Shanghai 200032, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul E.","family":"Kilgore","sequence":"additional","affiliation":[{"name":"International Vaccine Institute, Seoul 151-818, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung Ah","family":"Lim","sequence":"additional","affiliation":[{"name":"International Vaccine Institute, Seoul 151-818, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Song-Mei","family":"Wang","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeongseok","family":"Lee","sequence":"additional","affiliation":[{"name":"International Vaccine Institute, Seoul 151-818, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, School of Public Health, Fudan University, Shanghai 200032, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei-Qi","family":"Mo","sequence":"additional","affiliation":[{"name":"Center for Public Health and Infectious Disease, Institutes of Biomedical Sciences, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Batmunkh","family":"Nyambat","sequence":"additional","affiliation":[{"name":"International Vaccine Institute, Seoul 151-818, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing-Chen","family":"Ma","sequence":"additional","affiliation":[{"name":"Center for Public Health and Infectious Disease, Institutes of Biomedical Sciences, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael O.","family":"Favorov","sequence":"additional","affiliation":[{"name":"International Vaccine Institute, Seoul 151-818, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John D.","family":"Clemens","sequence":"additional","affiliation":[{"name":"International Vaccine Institute, Seoul 151-818, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","year":"2006"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1086\/528685"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2005.01.023"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(06)70466-2"},{"issue":"15","key":"7","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1001\/jama.283.15.2008","volume":"283","year":"2000","journal-title":"Journal of the American Medical Association"},{"key":"8","year":"2001"},{"issue":"2","key":"9","doi-asserted-by":"crossref","first-page":"233","DOI":"10.18433\/J3JP4B","volume":"12","year":"2009","journal-title":"Journal of Pharmacy & Pharmaceutical Sciences"},{"issue":"3","key":"10","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","volume":"7","year":"1986","journal-title":"Controlled Clinical Trials"},{"key":"11","first-page":"57","volume-title":"Combining estimates of a treatment difference across trials","year":"2002"},{"issue":"12, article e8540","key":"12","volume":"4","year":"2009","journal-title":"PloS One"},{"issue":"2","key":"13","doi-asserted-by":"crossref","first-page":"235","DOI":"10.5858\/134.2.235","volume":"134","year":"2010","journal-title":"Archives of Pathology and Laboratory Medicine"},{"issue":"38","key":"14","first-page":"1071","volume":"58","year":"2009","journal-title":"Morbidity and Mortality Weekly Report"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2009.02725.x"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1086\/430782"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1038\/nm1077"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-6-58"}],"container-title":["Interdisciplinary Perspectives on Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ipid\/2011\/146376.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ipid\/2011\/146376.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ipid\/2011\/146376.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T03:36:28Z","timestamp":1637638588000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/ipid\/2011\/146376\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":16,"alternative-id":["146376","146376"],"URL":"https:\/\/doi.org\/10.1155\/2011\/146376","relation":{},"ISSN":["1687-708X","1687-7098"],"issn-type":[{"value":"1687-708X","type":"print"},{"value":"1687-7098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}