{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T18:07:28Z","timestamp":1785002848531,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["PO1 AI-030731"],"award-info":[{"award-number":["PO1 AI-030731"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["K24 AI-071113"],"award-info":[{"award-number":["K24 AI-071113"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["PO1 AI-030731"],"award-info":[{"award-number":["PO1 AI-030731"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["K24 AI-071113"],"award-info":[{"award-number":["K24 AI-071113"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infectious Diseases in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To compare genital HSV shedding among HIV-positive and HIV-negative women.<jats:italic>Methods<\/jats:italic>. Women with and without known HIV infection who delivered at the University of Washington Medical Center between 1989\u20131996 had HSV serologies done as part of clinical care. Genital swabs from HSV-2-seropositive women were evaluated by real-time quantitative HSV DNA PCR.<jats:italic>Results<\/jats:italic>. HSV-2 seroprevalence was 71% and 30% among 75 HIV-positive and 3051 HIV-negative women, respectively, (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>.00<\/mml:mn><mml:mn>1<\/mml:mn><\/mml:mrow><\/mml:math>). HSV was detected at delivery in the genital tract of 30.8% of HIV-seropositive versus 9.5% of HIV-negative women (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mtext>RR<\/mml:mtext><mml:mo>=<\/mml:mo><mml:mn>3.2<\/mml:mn><\/mml:mrow><\/mml:math>, 95% CI 1.6 to 6.5,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>.00<\/mml:mn><mml:mn>1<\/mml:mn><\/mml:mrow><\/mml:math>). The number of virion copies shed per mL was similar (log\u20093.54 for HIV positive versus 3.90 for HIV negative,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>.99<\/mml:mn><\/mml:mrow><\/mml:math>).<jats:italic>Conclusions<\/jats:italic>. Our study demonstrated that HIV-, HSV-2-coinfected women are more likely to shed HSV at delivery.<\/jats:p>","DOI":"10.1155\/2011\/157680","type":"journal-article","created":{"date-parts":[[2011,3,27]],"date-time":"2011-03-27T19:32:08Z","timestamp":1301254328000},"page":"1-4","source":"Crossref","is-referenced-by-count":19,"title":["Genital HSV Detection among HIV-1-Infected Pregnant Women in Labor"],"prefix":"10.1155","volume":"2011","author":[{"given":"Janna","family":"Patterson","sequence":"first","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, University of Washington, P.O. 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Heather","family":"Watts","sequence":"additional","affiliation":[{"name":"Pediatric, Adolescent and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Rockville, MD 20847, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zane","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Washington, Seattle, WA 98195-6320, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence","family":"Corey","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, University of Washington, Seattle, WA 98195-6320, USA"},{"name":"Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA"},{"name":"Department of Medicine, University of Washington, Seattle, WA 98195-6320, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Wald","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, University of Washington, Seattle, WA 98195-6320, USA"},{"name":"Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA"},{"name":"Department of Medicine, University of Washington, Seattle, WA 98195-6320, USA"},{"name":"Department of Epidemiology, University of Washington, Seattle, WA 98195-6320, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1086\/315836"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1086\/317918"},{"issue":"6","key":"3","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1097\/01.AOG.0000185917.90004.7c","volume":"106","year":"2005","journal-title":"Obstetrics and Gynecology"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000251511.27725.5c"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1086\/314486"},{"issue":"11","key":"6","doi-asserted-by":"crossref","first-page":"845","DOI":"10.7326\/0003-4819-123-11-199512010-00006","volume":"123","year":"1995","journal-title":"Annals of Internal Medicine"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1258\/095646206775455711"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.2.203"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1542\/peds.108.2.230"},{"key":"10","first-page":"175A","volume":"11","year":"2004","journal-title":"Herpes"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2003.185"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)70214-X"},{"issue":"4","key":"13","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1128\/JCM.26.4.662-667.1988","volume":"26","year":"1988","journal-title":"Journal of Clinical Microbiology"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.7.2609-2611.2002"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3282fec42a"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3282f2a939"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.obstetgynecol.2003.08.015"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1258\/095646207782716965"},{"issue":"rr-7","key":"19","first-page":"1","volume":"44","year":"1995","journal-title":"Morbidity and Mortality Weekly Report Recommendations and Reports"},{"issue":"4","key":"20","first-page":"5s","volume":"104","year":"2005","journal-title":"Obstetrics and Gynecology"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0800260"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0904849"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32831db217"}],"container-title":["Infectious Diseases in Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/idog\/2011\/157680.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/idog\/2011\/157680.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/idog\/2011\/157680.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,17]],"date-time":"2020-06-17T16:43:44Z","timestamp":1592412224000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/idog\/2011\/157680\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":23,"alternative-id":["157680","157680"],"URL":"https:\/\/doi.org\/10.1155\/2011\/157680","relation":{},"ISSN":["1064-7449","1098-0997"],"issn-type":[{"value":"1064-7449","type":"print"},{"value":"1098-0997","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}