{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:37:30Z","timestamp":1788871050165,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","license":[{"start":{"date-parts":[[2011,3,3]],"date-time":"2011-03-03T00:00:00Z","timestamp":1299110400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"French Ministry of Foreign and European Affairs","award":["IRD-DSF"],"award-info":[{"award-number":["IRD-DSF"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemotherapy Research and Practice"],"published-print":{"date-parts":[[2011,3,3]]},"abstract":"<jats:p>\n                    <jats:italic>Pteleopsis hylodendron<\/jats:italic>\n                    (Combretaceae) is used in Cameroon and West Africa folk medicine for the treatment of various microbial infections (measles, chickenpox, and sexually transmitted diseases). The antibacterial properties of the methanolic extract and fractions from stem bark of\n                    <jats:italic>Pteleopsis hylodendron<\/jats:italic>\n                    were tested against three Gram-positive bacteria and eight Gram-negative bacteria using Agar-well diffusion and Broth microdilution methods. Antioxidant activities of the crude extract and fractions were investigated by DPPH radical scavenging activity and \u03b2-carotene-linoleic acid assays. The methanolic extract and some fractions exhibited antibacterial activities that varied between the bacterial species (ID = 0.00\u201325.00\u2009mm; MIC = 781\u201312500\u2009\u03bcg\/mL and 0.24\u20131000\u2009\u03bcg\/mL). The activity of the crude extract is, however, very weak compared to the reference antibiotics (MIC = 0.125\u2013128\u2009\u03bcg\/mL). Two fractions (F\n                    <jats:sub>E<\/jats:sub>\n                    and F\n                    <jats:sub>F<\/jats:sub>\n                    ) showed significant activity (MIC = 0.97\u2009\u03bcg\/mL) while\n                    <jats:italic>S. aureus<\/jats:italic>\n                    ATCC 25922 was almost resistant to all the tested fractions. In addition, the crude extract and some fractions showed good antioxidant potential with inhibition values ranging from 17.53 to 98.79%. These results provide promising baseline information for the potential use of this plant as well as some of the fractions in the treatment of infectious diseases and oxidative stress.\n                  <\/jats:p>","DOI":"10.1155\/2011\/218750","type":"journal-article","created":{"date-parts":[[2011,3,6]],"date-time":"2011-03-06T04:10:48Z","timestamp":1299384648000},"page":"1-7","source":"Crossref","is-referenced-by-count":2,"title":["Antibacterial and Antioxidant Properties of the Methanolic Extract of the Stem Bark of\n                    <i>Pteleopsis hylodendron<\/i>\n                    (Combretaceae)"],"prefix":"10.1155","volume":"2011","author":[{"given":"Aristide Laurel","family":"Mokale Kognou","sequence":"first","affiliation":[{"name":"Laboratory of Microbiology and Antimicrobial Substances, University of Dschang, P.O. Box 67 Dschang, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosalie Annie","family":"Ngono Ngane","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Douala, P.O. Box 24157 Douala, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jules Roger","family":"Kuiate","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiology and Antimicrobial Substances, University of Dschang, P.O. Box 67 Dschang, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin Luther","family":"Koanga Mogtomo","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Douala, P.O. Box 24157 Douala, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alembert","family":"Tchinda Tiabou","sequence":"additional","affiliation":[{"name":"Laboratory of Phytochemistry, Institute of Medical Research and Medicinal Plants Study, Ministry of Scientific Research and Innovation, P.O. Box 6163, Yaound\u00e9, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond Simplice","family":"Mouokeu","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiology and Antimicrobial Substances, University of Dschang, P.O. Box 67 Dschang, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucie","family":"Biyiti","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Yaound\u00e9 I, P.O. Box 812 Yaound\u00e9, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul Henri","family":"Amvam Zollo","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Yaound\u00e9 I, P.O. Box 812 Yaound\u00e9, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","first-page":"1532","volume":"11","year":"2003","journal-title":"Bioorganic and Medical Chemistry"},{"issue":"4","key":"2","first-page":"281","volume":"38","year":"1991","journal-title":"M\u00e9d\u00e9cine d\u2019Afrique Noire"},{"key":"3","first-page":"4","volume":"8","year":"2007","journal-title":"WHO"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-8741(03)00107-7"},{"key":"5","first-page":"286","volume":"9","year":"1996","journal-title":"Chemical Abstracts-Organic Chemistry"},{"key":"7","first-page":"12","volume":"25","year":"1983","journal-title":"Yaound\u00e9"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1055\/s-2001-14306"},{"key":"11","first-page":"47","volume":"6","year":"1991","journal-title":"Methods for Plant Biochemistry"},{"key":"12","year":"1975"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2004.11.016"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-8741(01)00350-6"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.687"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1002\/pca.611"},{"key":"17","year":"1999"},{"key":"18","first-page":"227","volume-title":"Introduction aux techniques d\u2019\u00e9tude des antibiotiques","year":"1990"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-8741(98)00184-6"},{"issue":"2","key":"20","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1574-6968.2002.tb11487.x","volume":"217","year":"2002","journal-title":"FEMS Microbiology Letters"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(99)00250-2"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2008.05.006"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-8741(97)00109-8"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1248\/cpb.55.1640"},{"issue":"4","key":"25","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1128\/CMR.12.4.564","volume":"12","year":"1999","journal-title":"Clinical Microbiology Reviews"},{"issue":"12","key":"26","doi-asserted-by":"crossref","first-page":"3875","DOI":"10.1016\/0031-9422(91)83426-L","volume":"30","year":"1991","journal-title":"Phytochemistry"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.3923\/jm.2008.414.422"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-8741(03)00006-0"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-8741(98)00130-5"},{"key":"30","first-page":"313","volume":"144","year":"2005","journal-title":"Bulletin de Soci\u00e9t\u00e9 de Pharmacie"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1001\/jama.297.8.842"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1016\/0891-5849(95)02227-9"},{"issue":"6","key":"33","doi-asserted-by":"crossref","first-page":"3406","DOI":"10.1128\/AEM.69.6.3406-3411.2003","volume":"69","year":"2003","journal-title":"Applied and Environmental Microbiology"},{"issue":"8","key":"34","first-page":"1200","volume":"6","year":"2007","journal-title":"Cancer Biology and Therapy"}],"container-title":["Chemotherapy Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/2011\/218750.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2011\/218750.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2011\/218750.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,8]],"date-time":"2020-12-08T20:34:48Z","timestamp":1607459688000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cherp\/2011\/218750\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,3]]},"references-count":31,"alternative-id":["218750","218750"],"URL":"https:\/\/doi.org\/10.1155\/2011\/218750","relation":{},"ISSN":["2090-2107","2090-2115"],"issn-type":[{"value":"2090-2107","type":"print"},{"value":"2090-2115","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,3]]}}}