{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T10:44:01Z","timestamp":1786358641588,"version":"build-2736575974"},"reference-count":14,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/100011081","name":"Canadian Rheumatology Association","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100011081","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Alberta Innovations Health Solution Health Scholar award"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Rheumatology"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To describe obstetrical and neonatal outcomes in Canadian women with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE).<jats:italic>Methods<\/jats:italic>. An administrative database of hospitalizations for neonatal delivery (1998\u20132009) from Calgary, Alberta was searched to identify women with RA (38 pregnancies) or SLE (95 pregnancies), and women from the general population matched on maternal age and year of delivery (150 and 375 pregnancies, resp.). Conditional logistic regression was used to calculate odds ratios (OR) for maternal and neonatal outcomes, adjusting for parity.<jats:italic>Results<\/jats:italic>. Women with SLE had increased odds for preeclampsia or eclampsia (SLE OR 2.16 (95% CI 1.10\u20134.21;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.024<\/mml:mn><\/mml:mrow><\/mml:math>); RA OR 2.33 (95% CI 0.76\u20137.14;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.138<\/mml:mn><\/mml:mrow><\/mml:math>)). Women with SLE had increased odds for cesarean section after adjustment for dysfunctional labour, instrumentation and previous cesarean section (OR 3.47 (95% CI 1.67\u20137.22;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:mrow><\/mml:math>)). Neonates born to women with SLE had increased odds of prematurity (SLE OR 6.17 (95% CI 3.28\u201311.58;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:mrow><\/mml:math>); RA OR 2.66 (95% CI 0.90\u20137.84;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.076<\/mml:mn><\/mml:mrow><\/mml:math>)) and of SGA (SLE OR 2.54 (95% CI 1.42\u20134.55;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.002<\/mml:mn><\/mml:mrow><\/mml:math>); RA OR 2.18 (95% CI 0.84\u20135.66;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.108<\/mml:mn><\/mml:mrow><\/mml:math>)) after adjusting for maternal hypertension. There was no excess risk of congenital defects in neonates.<jats:italic>Conclusions<\/jats:italic>. There is increased obstetrical and neonatal morbidity in Canadian women with RA or SLE.<\/jats:p>","DOI":"10.1155\/2011\/345727","type":"journal-article","created":{"date-parts":[[2011,10,19]],"date-time":"2011-10-19T19:01:47Z","timestamp":1319050907000},"page":"1-6","source":"Crossref","is-referenced-by-count":56,"title":["Canadian Pregnancy Outcomes in Rheumatoid Arthritis and Systemic Lupus Erythematosus"],"prefix":"10.1155","volume":"2011","author":[{"given":"Cheryl","family":"Barnabe","sequence":"first","affiliation":[{"name":"Department of Medicine, University of Calgary, Calgary, AB, Canada T2N 4N1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter D.","family":"Faris","sequence":"additional","affiliation":[{"name":"Alberta Bone & Joint Health Institute, Calgary, AB, Canada T2N 4Z6"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hude","family":"Quan","sequence":"additional","affiliation":[{"name":"Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada T2N 4N1"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2009.11.015"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2010.02250.x"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1002\/art.21663"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.03.012"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/s10995-006-0073-3"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.105262"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1002\/art.30210"},{"key":"8","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1097\/01.AOG.0000126279.87151.e1","volume":"103","year":"2004","journal-title":"Obstetrics and Gynecology"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2010.02239.x"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.090872"},{"issue":"2","key":"12","first-page":"355","volume":"28","year":"2001","journal-title":"Journal of Rheumatology"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1002\/art.24003"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2007.01.001"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-6773.2005.00444.x"}],"container-title":["International Journal of Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijr\/2011\/345727.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijr\/2011\/345727.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijr\/2011\/345727.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,7]],"date-time":"2020-05-07T00:46:29Z","timestamp":1588812389000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/ijr\/2011\/345727\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":14,"alternative-id":["345727","345727"],"URL":"https:\/\/doi.org\/10.1155\/2011\/345727","relation":{},"ISSN":["1687-9260","1687-9279"],"issn-type":[{"value":"1687-9260","type":"print"},{"value":"1687-9279","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}