{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T06:21:46Z","timestamp":1759990906911,"version":"3.41.2"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,6,9]],"date-time":"2011-06-09T00:00:00Z","timestamp":1307577600000},"content-version":"vor","delay-in-days":159,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:p><jats:italic>Streptococcus pneumoniae<\/jats:italic>, one of the most common gram\u2010positive pathogens to colonize the human upper respiratory tract, is responsible for many severe infections, including meningitis and bacteremia. A 23\u2010valent pneumococcal vaccine is available to protect against the 23 <jats:italic>S. pneumoniae<\/jats:italic> serotypes responsible for 90% of reported bacteremic infections. Unfortunately, current <jats:italic>S. pneumoniae<\/jats:italic> serotype testing requires a large panel of expensive antisera, assay results may be subjective, and serotype cross\u2010reactions are common. For this study, we designed an oligonucleotide\u2010based DNA microarray to identify glycosyltransferase gene sequences specific to each vaccine\u2010related serotype. Out of 56 isolates representing different serotypes, only one isolate, representing serotype 23A, was not detected correctly as it could not be distinguished from serotype 23F. Our data suggest that the microarray provides a more cost\u2010effective and reliable way of monitoring pneumococcal capsular types.<\/jats:p>","DOI":"10.1155\/2011\/352736","type":"journal-article","created":{"date-parts":[[2011,6,10]],"date-time":"2011-06-10T07:18:59Z","timestamp":1307690339000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["A New Microarray System to Detect <i>Streptococcus pneumoniae<\/i> Serotypes"],"prefix":"10.1155","volume":"2011","author":[{"given":"Yuka","family":"Tomita","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Okamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Testuya","family":"Yagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinori","family":"Hasegawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michio","family":"Ohta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,6,9]]},"reference":[{"key":"e_1_2_7_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61114-4"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra011994"},{"key":"e_1_2_7_3_2","first-page":"1","article-title":"Preventing pneumococcal disease among infants and young children: recommendations of the Advisory Committee on Immunization Practices (ACIP)","volume":"49","author":"CDC","year":"2000","journal-title":"Morbidity and Mortality Weekly Report"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1086\/514205"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.33.10.2759-2762.1995"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/3.2.246"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/9781555816537.ch3"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0923-2508(00)00173-X"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.0020031"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02388078"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00837-07"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.6.2378-2384.2003"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.44.5.1887-1891.2006"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.05277-0"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.45924-0"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.4.1319-1323.2000"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.2.601-607.2003"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.44.1.124-131.2006"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01076-07"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.6.2656-2661.2005"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mimet.2006.07.001"},{"key":"e_1_2_7_22_2","first-page":"19","volume-title":"Pneumococcal Vaccines","author":"M\u00e4kel\u00e4 P. 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