{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T16:41:28Z","timestamp":1740156088810,"version":"3.37.3"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology Research and Practice"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Recent studies have demonstrated that there exists a great variation in the lymphatic drainage in patients with malignant melanoma. Some patients have drainage to lymph nodes outside of conventional nodal basins. The lymph nodes that exist between a primary melanoma and its regional nodal basin are defined \u201cinterval nodes\u201d. Interval node occurs in a small minority of patients with forearm melanoma. We report our experience of the Melanoma Unit of University Hospital Spedali Civili Brescia, Italy.<jats:italic>Methods<\/jats:italic>. Lymphatic mapping using cutaneous lymphoscintigraphy (LS) has become a standard preoperative diagnostic procedure to locate the sentinel lymph nodes (SLNs) in cutaneous melanoma. We used LS to identify sentinel lymph nodes biopsy (SLNB) in 480 patients.<jats:italic>Results<\/jats:italic>. From over 2100 patients affected by cutaneous melanoma, we identified 2 interval nodes in 480 patients with SLNB . The melanomas were both located in the left forearm. The interval nodes were also both located in the left arm.<jats:italic>Conclusion<\/jats:italic>. The combination of preoperative LS and intraoperative hand-held gamma detecting probe plays a remarkable role in identifying these uncommon lymph node locations. Knowledge of the unusual drainage patterns will help to ensure the accuracy and the completeness of sentinel nodes identification.<\/jats:p>","DOI":"10.1155\/2011\/506790","type":"journal-article","created":{"date-parts":[[2011,5,4]],"date-time":"2011-05-04T15:31:28Z","timestamp":1304523088000},"page":"1-3","source":"Crossref","is-referenced-by-count":4,"title":["Interval Sentinel Lymph Nodes: An Unusual Localization in Patients with Cutaneous Melanoma"],"prefix":"10.1155","volume":"2011","author":[{"given":"A. M.","family":"Manganoni","sequence":"first","affiliation":[{"name":"Department of Dermatology, University Hospital Spedali Civili, 25123 Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Farfaglia","sequence":"additional","affiliation":[{"name":"Department of II Surgery, University Hospital Spedali Civili, 25123 Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5630-4519","authenticated-orcid":true,"given":"E.","family":"Sereni","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University Hospital Spedali Civili, 25123 Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Farisoglio","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University Hospital Spedali Civili, 25123 Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Pizzocaro","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, University Hospital Spedali Civili, 25123 Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Marocolo","sequence":"additional","affiliation":[{"name":"Department of I Pathology, University Hospital Spedali Civili, 25123 Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Gavazzoni","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University Hospital Spedali Civili, 25123 Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Pavoni","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University Hospital Spedali Civili, 25123 Brescia, 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