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Total acidity, volume of gastric acid secretion, total acid output, and pepsin activity show significant reduction, when compared with the control group. The present study confirmed that chloroform fraction showed the significant activity at lower doses compared to parent extract. The mechanism can be attributed to decrease in gastric acid secretary activity along with strengthening of mucosal defensive mechanism by prostaglandin synthesis and antioxidant potential.<\/jats:p>","DOI":"10.1155\/2011\/541624","type":"journal-article","created":{"date-parts":[[2011,2,24]],"date-time":"2011-02-24T19:33:04Z","timestamp":1298575984000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Gastroprotective Effect of <i>Rubia cordifolia<\/i> Linn. on Aspirin Plus Pylorus\u2010Ligated Ulcer"],"prefix":"10.1155","volume":"2011","author":[{"given":"R. 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