{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T15:43:03Z","timestamp":1788622983869,"version":"build-2803163510"},"reference-count":8,"publisher":"Wiley","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institute of Health Research","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Vision Science Research Program"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. To present a series of retinal disease cases that were imaged by spectral domain optical coherence tomography (SD-OCT) in order to illustrate the potential and limitations of this new imaging modality.<jats:italic>Methods<\/jats:italic>. The series comprised four selected cases (one case each) of age-related macular degeneration (ARMD), diabetic retinopathy (DR), central retinal artery occlusion (CRAO), and branch retinal vein occlusion (BRVO). Patients were imaged using the Heidelberg Spectralis (Heidelberg Engineering, Germany) in SD-OCT mode. Patients also underwent digital fundus photography and clinical assessment.<jats:italic>Results<\/jats:italic>. SD-OCT imaging of a case of age-related macular degeneration revealed a subfoveal choroidal neovascular membrane with detachment of the retinal pigment epithelium (RPE) and neurosensory retina. Using SD-OCT, the cases of DR and BRVO both exhibited macular edema with cystoid spaces visible in the outer retina.<jats:italic>Conclusions<\/jats:italic>. The ability of SD-OCT to clearly and objectively elucidate subtle morphological changes within the retinal layers provides information that can be used to formulate diagnoses with greater confidence.<\/jats:p>","DOI":"10.1155\/2011\/764183","type":"journal-article","created":{"date-parts":[[2011,9,29]],"date-time":"2011-09-29T15:03:47Z","timestamp":1317308627000},"page":"1-6","source":"Crossref","is-referenced-by-count":27,"title":["High-Resolution Optical Coherence Tomography Retinal Imaging: A Case Series Illustrating Potential and Limitations"],"prefix":"10.1155","volume":"2011","author":[{"given":"Olena","family":"Puzyeyeva","sequence":"first","affiliation":[{"name":"Retina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada M5T 2S8"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wai Ching","family":"Lam","sequence":"additional","affiliation":[{"name":"Retina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada M5T 2S8"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John G.","family":"Flanagan","sequence":"additional","affiliation":[{"name":"Retina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada M5T 2S8"},{"name":"School of Optometry, University of Waterloo, Waterloo, ON, Canada N2L 3G1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael H.","family":"Brent","sequence":"additional","affiliation":[{"name":"Retina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada M5T 2S8"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert G.","family":"Devenyi","sequence":"additional","affiliation":[{"name":"Retina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada M5T 2S8"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark S.","family":"Mandelcorn","sequence":"additional","affiliation":[{"name":"Retina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada M5T 2S8"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tien","family":"Wong","sequence":"additional","affiliation":[{"name":"Retina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada M5T 2S8"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Hudson","sequence":"additional","affiliation":[{"name":"Retina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada M5T 2S8"},{"name":"School of Optometry, University of Waterloo, Waterloo, ON, Canada N2L 3G1"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.07-0895"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2007.07.005"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1117\/1.1482379"},{"issue":"21","key":"5","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1364\/OL.28.002067","volume":"28","year":"2003","journal-title":"Optics Letters"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.3928\/15428877-20090430-20"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.3928\/15428877-20090430-23"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2009.02017.x"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.2009.01602.x"}],"container-title":["Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2011\/764183.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2011\/764183.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2011\/764183.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T03:11:04Z","timestamp":1497928264000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/joph\/2011\/764183\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":8,"alternative-id":["764183","764183"],"URL":"https:\/\/doi.org\/10.1155\/2011\/764183","relation":{},"ISSN":["2090-004X","2090-0058"],"issn-type":[{"value":"2090-004X","type":"print"},{"value":"2090-0058","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}