{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T04:54:57Z","timestamp":1789966497786,"version":"4.0.1"},"reference-count":201,"publisher":"Wiley","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Multiple Sclerosis International"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>Following emerging evidence that neurodegenerative processes in multiple sclerosis (MS) are present from its early stages, an intensive scientific interest has been directed to biomarkers of neuro-axonal damage in body fluids of MS patients. Recent research has introduced new candidate biomarkers but also elucidated pathogenetic and clinical relevance of the well-known ones. This paper reviews the existing data on blood and cerebrospinal fluid biomarkers of neuroaxonal damage in MS and highlights their relation to clinical parameters, as well as their potential predictive value to estimate future disease course, disability, and treatment response. Strategies for future research in this field are suggested.<\/jats:p>","DOI":"10.1155\/2011\/767083","type":"journal-article","created":{"date-parts":[[2011,5,2]],"date-time":"2011-05-02T19:32:00Z","timestamp":1304364720000},"page":"1-18","source":"Crossref","is-referenced-by-count":16,"title":["Cerebrospinal Fluid and Blood Biomarkers of Neuroaxonal Damage in Multiple Sclerosis"],"prefix":"10.1155","volume":"2011","author":[{"given":"Irena","family":"Dujmovic","sequence":"first","affiliation":[{"name":"Neurology Clinic, Clinical Center of Serbia, Dr Subotica 6, P.O. Box 12, 11129 Belgrade 102, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2009.41"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.9.1345"},{"key":"3","year":"1880"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/119.3.701"},{"issue":"6","key":"5","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1093\/brain\/119.6.2009","volume":"119","year":"1996","journal-title":"Brain"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199801293380502"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-199906000-00008"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(200012)48:6<893::AID-ANA10>3.0.CO;2-B"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.30.051606.094313"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/120.3.393"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1002\/ana.1123"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2008.08.009"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1097\/NEN.0b013e3181a19a5a"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-003-0243-9"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-006-0408-4"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0011625"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-200106000-00003"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(02)00069-2"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000275229.13012.32"},{"issue":"3","key":"20","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1177\/135245859800400310","volume":"4","year":"1998","journal-title":"Multiple Sclerosis"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(04)00964-0"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh176"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2010.01.004"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2010.01.006"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1191\/135248506ms1263oa"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.2174\/092986707781368478"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awq035"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1159\/000109935"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000344417.42972.54"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awq076"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000336916.38629.43"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1191\/1352458503ms917oa"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awp070"},{"key":"34","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/j.1759-1961.2009.00003.x","volume":"1","year":"2010","journal-title":"Clinical and Experimental Neuroimmunology"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(99)00178-1"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0901496106"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1007\/s00109-010-0632-3"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-2236(02)02154-9"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181c97c8f"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1007\/400_2008_15"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5728(99)00212-X"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(02)01112-7"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2008.06.029"},{"issue":"60","key":"44","first-page":"375","year":"2000","journal-title":"Journal of Neural Transmission"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1177\/1352458510364196"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.2008.00987.x"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-200306000-00003"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2004.09.001"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20165"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1097\/NEN.0b013e3181f3a5b1"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.1097\/NEN.0b013e3181d60ddb"},{"key":"52","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21935"},{"key":"53","doi-asserted-by":"publisher","DOI":"10.4061\/2010\/548145"},{"key":"54","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181a0fe3f"},{"key":"55","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1146\/annurev.ne.19.030196.001155","volume":"19","year":"1996","journal-title":"Annual Review of Neuroscience"},{"key":"56","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.21803"},{"key":"57","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2005.03.015"},{"issue":"2","key":"58","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0165-5728(87)90049-X","volume":"14","year":"1987","journal-title":"Journal of Neuroimmunology"},{"key":"59","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0079-6603(08)60823-5","volume":"61","year":"1998","journal-title":"Progress in Nucleic Acid Research and Molecular Biology"},{"key":"60","doi-asserted-by":"publisher","DOI":"10.1126\/science.279.5350.514"},{"issue":"3","key":"61","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1136\/jnnp.64.3.402","volume":"64","year":"1998","journal-title":"Journal of Neurology Neurosurgery and Psychiatry"},{"key":"62","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2004.043315"},{"key":"67","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5728(01)00455-6"},{"issue":"12","key":"66","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1212\/01.WNL.0000098880.19793.B6","volume":"61","year":"2003","journal-title":"Neurology"},{"issue":"9","key":"68","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1212\/01.WNL.0000142988.49341.D1","volume":"63","year":"2004","journal-title":"Neurology"},{"issue":"2","key":"65","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1212\/01.WNL.0000041496.58127.E3","volume":"60","year":"2003","journal-title":"Neurology"},{"key":"70","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0404.2003.00197.x"},{"issue":"5","key":"71","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1046\/j.1471-4159.1996.67052013.x","volume":"67","year":"1996","journal-title":"Journal of Neurochemistry"},{"key":"73","doi-asserted-by":"publisher","DOI":"10.1191\/1352458504ms1020oa"},{"key":"75","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000256820.26489.17"},{"key":"72","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2003.017236"},{"key":"74","doi-asserted-by":"publisher","DOI":"10.1177\/1352458507082061"},{"key":"63","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(03)03219-0"},{"issue":"9","key":"64","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1212\/WNL.58.9.1372","volume":"58","year":"2002","journal-title":"Neurology"},{"key":"69","doi-asserted-by":"publisher","DOI":"10.1177\/1352458509359725"},{"key":"76","doi-asserted-by":"publisher","DOI":"10.1191\/135248505ms1277oa"},{"key":"77","doi-asserted-by":"publisher","DOI":"10.1191\/1352458504ms1021sr"},{"key":"78","doi-asserted-by":"publisher","DOI":"10.1191\/1352458505ms1218oa"},{"key":"82","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2006.00794.x"},{"key":"83","doi-asserted-by":"publisher","DOI":"10.1191\/1352458504ms1100oa"},{"issue":"1","key":"84","doi-asserted-by":"crossref","first-page":"23","DOI":"10.14712\/fb2009055010023","volume":"55","year":"2009","journal-title":"Folia Biologica"},{"key":"85","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-006-0185-0"},{"key":"89","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2008.02223.x"},{"key":"157","doi-asserted-by":"publisher","DOI":"10.1007\/s10875-007-9091-1"},{"issue":"2-3","key":"79","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0165-5728(89)90175-6","volume":"21","year":"1989","journal-title":"Journal of Neuroimmunology"},{"key":"80","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2004.12.018"},{"issue":"3","key":"81","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/01.wco.0000169737.99040.31","volume":"18","year":"2005","journal-title":"Current Opinion in Neurology"},{"key":"86","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-679X(10)97001-5"},{"key":"87","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.cellbio.16.1.89"},{"issue":"2","key":"88","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1139\/o97-032","volume":"75","year":"1997","journal-title":"Biochemistry and Cell Biology"},{"key":"90","doi-asserted-by":"publisher","DOI":"10.1006\/clin.1995.1028"},{"key":"91","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2008.02133.x"},{"key":"92","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.26.16319"},{"issue":"8","key":"93","doi-asserted-by":"crossref","first-page":"5271","DOI":"10.1016\/S0021-9258(17)42985-1","volume":"259","year":"1984","journal-title":"Journal of Biological Chemistry"},{"issue":"20","key":"94","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1056\/NEJM199205143262006","volume":"326","year":"1992","journal-title":"New England Journal of Medicine"},{"key":"95","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-10-107"},{"key":"96","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2194"},{"key":"97","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.01558"},{"key":"98","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M700192200"},{"key":"99","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-009-0515-2"},{"key":"100","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn119"},{"key":"101","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-010-0671-4"},{"key":"102","doi-asserted-by":"publisher","DOI":"10.1191\/1352458505ms1159oa"},{"key":"103","doi-asserted-by":"publisher","DOI":"10.1191\/1352458506ms1288sr"},{"key":"104","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2008.02.064"},{"issue":"6","key":"105","first-page":"971","volume":"29","year":"2008","journal-title":"Neuroendocrinology Letters"},{"issue":"4","key":"106","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1159\/000008181","volume":"43","year":"2000","journal-title":"European Neurology"},{"key":"107","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-004-0336-0"},{"key":"108","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-005-0327-z"},{"key":"109","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2007.00782.x"},{"key":"110","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0404.2002.01370.x"},{"key":"111","doi-asserted-by":"publisher","DOI":"10.1177\/08830738050200100801"},{"key":"112","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2004.03.039"},{"key":"113","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(01)01556-7"},{"key":"114","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2010.107"},{"key":"115","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M409954200"},{"key":"116","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-009-5382-1"},{"key":"117","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0082(03)00089-3"},{"issue":"4","key":"118","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1073\/pnas.87.4.1561","volume":"87","year":"1990","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"119","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-003-0170-7"},{"issue":"2","key":"120","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/glia.440150206","volume":"15","year":"1995","journal-title":"Glia"},{"key":"121","doi-asserted-by":"publisher","DOI":"10.1177\/1352458508100031"},{"issue":"1","key":"122","doi-asserted-by":"crossref","first-page":"59","DOI":"10.2217\/17520363.1.1.59","volume":"1","year":"2007","journal-title":"Biomarkers in Medicine"},{"key":"123","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0891-08.2008"},{"key":"124","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2010.06.007"},{"key":"125","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2010.187"},{"issue":"9","key":"126","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1212\/WNL.58.9.1415","volume":"58","year":"2002","journal-title":"Neurology"},{"key":"127","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10052"},{"key":"128","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2006.12.003"},{"key":"129","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A0774"},{"key":"130","doi-asserted-by":"publisher","DOI":"10.1191\/1352458505ms1234oa"},{"key":"131","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-005-0964-z"},{"key":"132","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2254"},{"key":"133","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-006-0474-7"},{"issue":"1","key":"134","first-page":"35","volume":"157","year":"2001","journal-title":"Revue Neurologique"},{"key":"135","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/121.8.1469"},{"issue":"1","key":"136","first-page":"65","volume":"58","year":"2001","journal-title":"Archives of Neurology"},{"key":"137","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-002-0790-5"},{"key":"138","doi-asserted-by":"publisher","DOI":"10.1007\/s004150170052"},{"key":"185","doi-asserted-by":"publisher","DOI":"10.1191\/1352458504ms1089oa"},{"key":"139","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-006-0415-5"},{"key":"159","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(94)90264-X"},{"key":"162","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2006.11.012"},{"issue":"4","key":"160","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1136\/jnnp.63.4.446","volume":"63","year":"1997","journal-title":"Journal of Neurology Neurosurgery and Psychiatry"},{"key":"140","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/0076-6879(86)28109-4","volume":"128","year":"1986","journal-title":"Methods in Enzymology"},{"key":"141","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/186813"},{"issue":"7","key":"142","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1038\/labinvest.3780307","volume":"81","year":"2001","journal-title":"Laboratory Investigation"},{"issue":"1","key":"143","first-page":"46","volume":"18","year":"1988","journal-title":"Annals of Clinical and Laboratory Science"},{"key":"144","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(91)90070-S"},{"issue":"4","key":"145","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1177\/135245850000600403","volume":"6","year":"2000","journal-title":"Multiple Sclerosis"},{"key":"146","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.61.4.536"},{"key":"147","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2009.01278.x"},{"issue":"5","key":"148","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1212\/WNL.57.5.853","volume":"57","year":"2001","journal-title":"Neurology"},{"key":"149","doi-asserted-by":"publisher","DOI":"10.1191\/1352458505ms1207oa"},{"issue":"1","key":"150","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1001\/archneur.60.1.65","volume":"60","year":"2003","journal-title":"Archives of Neurology"},{"key":"151","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2009.02603.x"},{"key":"152","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000264004.62612.44"},{"key":"153","doi-asserted-by":"publisher","DOI":"10.1177\/1352458509348512"},{"key":"154","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(98)00118-X"},{"issue":"7","key":"155","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1093\/clinchem\/33.7.1155","volume":"33","year":"1987","journal-title":"Clinical Chemistry"},{"key":"156","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2008.02239.x"},{"issue":"4","key":"158","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1155\/2006\/509476","volume":"22","year":"2006","journal-title":"Disease Markers"},{"key":"161","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2006.01145.x"},{"issue":"6","key":"163","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1093\/clinchem\/38.6.813","volume":"38","year":"1992","journal-title":"Clinical Chemistry"},{"key":"164","doi-asserted-by":"publisher","DOI":"10.1080\/00365510410007035"},{"key":"165","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0082(97)00043-9"},{"key":"166","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.2006.00730.x"},{"key":"167","doi-asserted-by":"publisher","DOI":"10.1080\/00365510802651858"},{"key":"168","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2005.07.010"},{"key":"169","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(00)01466-X"},{"key":"172","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(02)00887-X"},{"key":"175","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(03)00667-0"},{"key":"173","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2004.034"},{"key":"184","doi-asserted-by":"publisher","DOI":"10.1007\/s004150200074"},{"issue":"4","key":"183","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1212\/WNL.57.4.722","volume":"57","year":"2001","journal-title":"Neurology"},{"key":"186","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-004-0524-y"},{"issue":"5","key":"170","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/S0022-2275(20)32393-2","volume":"41","year":"2000","journal-title":"Journal of Lipid Research"},{"key":"171","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000120374.59826.1b"},{"key":"174","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M200434-JLR200"},{"issue":"5","key":"176","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1111\/j.1471-4159.1982.tb07928.x","volume":"38","year":"1982","journal-title":"Journal of Neurochemistry"},{"key":"177","doi-asserted-by":"publisher","DOI":"10.1159\/000008054"},{"issue":"2","key":"178","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S0002-9440(10)63322-6","volume":"165","year":"2004","journal-title":"American Journal of Pathology"},{"key":"179","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.200700641"},{"key":"180","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2010.04.004"},{"key":"181","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2009.02595.x"},{"key":"182","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(199911)46:5<774::AID-ANA14>3.0.CO;2-N"},{"key":"187","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(03)00083-2"},{"issue":"9207","key":"188","first-page":"901","volume":"355","year":"2000","journal-title":"Lancet"},{"key":"189","doi-asserted-by":"publisher","DOI":"10.1191\/1352458504ms1023oa"},{"key":"190","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.200300715"},{"key":"191","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5728(92)90178-N"},{"key":"192","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200303240-00005"},{"key":"193","doi-asserted-by":"publisher","DOI":"10.1021\/pr0504788"},{"key":"194","doi-asserted-by":"publisher","DOI":"10.1002\/prca.200700315"},{"key":"195","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2007.04985.x"},{"key":"196","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20071053"},{"key":"197","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0007624"},{"key":"198","doi-asserted-by":"publisher","DOI":"10.1586\/14737159.8.4.479"},{"key":"199","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2009.04.010"},{"key":"200","doi-asserted-by":"publisher","DOI":"10.1016\/j.jim.2009.09.014"},{"key":"201","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181c47cc2"}],"container-title":["Multiple Sclerosis International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/msi\/2011\/767083.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/msi\/2011\/767083.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/msi\/2011\/767083.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T10:10:20Z","timestamp":1741169420000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/msi\/2011\/767083\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":201,"alternative-id":["767083","767083"],"URL":"https:\/\/doi.org\/10.1155\/2011\/767083","relation":{},"ISSN":["2090-2654","2090-2662"],"issn-type":[{"value":"2090-2654","type":"print"},{"value":"2090-2662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}