{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:22:33Z","timestamp":1788870153866,"version":"build-2803163510"},"reference-count":10,"publisher":"Wiley","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NO1 AI40029"],"award-info":[{"award-number":["NO1 AI40029"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5 T32 AR007472-21"],"award-info":[{"award-number":["5 T32 AR007472-21"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NO1 AI40029"],"award-info":[{"award-number":["NO1 AI40029"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5 T32 AR007472-21"],"award-info":[{"award-number":["5 T32 AR007472-21"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100003980","name":"National Eczema Association","doi-asserted-by":"publisher","award":["NO1 AI40029"],"award-info":[{"award-number":["NO1 AI40029"]}],"id":[{"id":"10.13039\/100003980","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100003980","name":"National Eczema Association","doi-asserted-by":"publisher","award":["5 T32 AR007472-21"],"award-info":[{"award-number":["5 T32 AR007472-21"]}],"id":[{"id":"10.13039\/100003980","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology Research and Practice"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>\n                    <jats:italic>Background<\/jats:italic>\n                    . Eczema herpeticum (EH) is a potentially serious, systemic complication in subjects with atopic dermatitis (AD) caused by herpes simplex virus (HSV). The innate immune dysregulation that predisposes these subjects to cutaneous viral infections is not well understood. We tested the hypothesis that defects in mannan-binding lectin (MBL) may be associated with an increased risk of EH.\n                    <jats:italic>Methods<\/jats:italic>\n                    . We evaluated serum MBL levels and functional activity in 13\u2009AD subjects with a history of EH (EH+) and 21\u2009AD subjects with no history of EH (EH\u2212). MBL levels were detected by enzyme immunoassay. MBL pathway functional activity was evaluated by determining MBL C4b deposition capacity.\n                    <jats:italic>Results<\/jats:italic>\n                    . We found no statistical difference in MBL serum levels or function between EH+ and EH\u2212 groups.\n                    <jats:italic>Conclusion<\/jats:italic>\n                    . Considering the limitations of this study (e.g., small samples size) our findings suggest that MBL defects do not play a role in EH.\n                  <\/jats:p>","DOI":"10.1155\/2011\/769890","type":"journal-article","created":{"date-parts":[[2011,11,10]],"date-time":"2011-11-10T14:01:18Z","timestamp":1320933678000},"page":"1-3","source":"Crossref","is-referenced-by-count":1,"title":["Mannan-Binding Lectin Levels and Activity Are Not Altered in Atopic Dermatitis Patients with a History of Eczema Herpeticum"],"prefix":"10.1155","volume":"2011","author":[{"given":"Kemp W.","family":"Bundy","sequence":"first","affiliation":[{"name":"Division of Allergy, Immunology, Rheumatology, University of Rochester Medical Center, Rochester, NY 14642, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura Y.","family":"McGirt","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Johns Hopkins University, Baltimore, MD 21205, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lora G.","family":"Bankova","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Johns Hopkins University, Baltimore, MD 21205, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Wollenberg","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy, Ludwig Maximilian University of Munich, 80539 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa A.","family":"Beck","sequence":"additional","affiliation":[{"name":"Division of Allergy, Immunology, Rheumatology, University of Rochester Medical Center, Rochester, NY 14642, USA"},{"name":"Department of Dermatology, University of Rochester Medical Center, 601 Elmwood Avenue, P.O. Box 697, Rochester, NY 14642, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"De Benedetto","sequence":"additional","affiliation":[{"name":"Division of Allergy, Immunology, Rheumatology, University of Rochester Medical Center, Rochester, NY 14642, USA"},{"name":"Department of Dermatology, University of Rochester Medical Center, 601 Elmwood Avenue, P.O. Box 697, Rochester, NY 14642, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-007-0032-9"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2003.07.001"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2009.05.020"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2005.12.1345"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.02.014"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.humimm.2006.02.030"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.2009.00789.x"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.humimm.2009.01.022"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1999.02638.x"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.144.3.412"}],"container-title":["Dermatology Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/drp\/2011\/769890.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/drp\/2011\/769890.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/drp\/2011\/769890.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,4]],"date-time":"2016-08-04T13:54:54Z","timestamp":1470318894000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/drp\/2011\/769890\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":10,"alternative-id":["769890","769890"],"URL":"https:\/\/doi.org\/10.1155\/2011\/769890","relation":{},"ISSN":["1687-6105","1687-6113"],"issn-type":[{"value":"1687-6105","type":"print"},{"value":"1687-6113","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}