{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:48:20Z","timestamp":1760122100542},"reference-count":9,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Nephrology"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Leptospirosis is a spirochetal zoonosis with complex clinical features including renal and liver failure.<jats:italic>Case report<\/jats:italic>. We report the case of a Swiss fisherman presenting with leptospirosis. After initial improvement, refractory septic shock and severe liver and kidney failure developed. The expected mortality was estimated at 90% with clinical scores. The patient underwent plasma exchanges and high-volume hemofiltration (HVHF) with complete recovery of hepatic and kidney functions.<jats:italic>Discussion<\/jats:italic>. Plasma exchanges and HVHF may confer survival benefit on patients with severe leptospirosis, refractory septic shock, and multiple-organ failure.<\/jats:p>","DOI":"10.1155\/2011\/817414","type":"journal-article","created":{"date-parts":[[2011,9,13]],"date-time":"2011-09-13T17:30:57Z","timestamp":1315935057000},"page":"1-3","source":"Crossref","is-referenced-by-count":6,"title":["Severe Leptospirosis with Multiple Organ Failure Successfully Treated by Plasma Exchange and High-Volume Hemofiltration"],"prefix":"10.1155","volume":"2011","author":[{"given":"Vincent","family":"Bourquin","sequence":"first","affiliation":[{"name":"Service de N\u00e9phrologie, D\u00e9partement de M\u00e9decine Interne, H\u00f4pitaux Universitaires de Gen\u00e8ve, 1205 Gen\u00e8ve, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bel\u00e9n","family":"Ponte","sequence":"additional","affiliation":[{"name":"Service de N\u00e9phrologie, D\u00e9partement de M\u00e9decine Interne, H\u00f4pitaux Universitaires de Gen\u00e8ve, 1205 Gen\u00e8ve, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard","family":"Hirschel","sequence":"additional","affiliation":[{"name":"Service des Maladies Infectieuses, D\u00e9partement de M\u00e9decine Interne, H\u00f4pitaux Universitaires de Gen\u00e8ve, 1205 Gen\u00e8ve, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e9r\u00f4me","family":"Pugin","sequence":"additional","affiliation":[{"name":"Service des Soins Intensifs, D\u00e9partement d'Anesth\u00e9siologie, de Pharmacologie et des Soins Intensifs, H\u00f4pitaux Universitaires de Gen\u00e8ve, 1205 Gen\u00e8ve, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre-Yves","family":"Martin","sequence":"additional","affiliation":[{"name":"Service de N\u00e9phrologie, D\u00e9partement de M\u00e9decine Interne, H\u00f4pitaux Universitaires de Gen\u00e8ve, 1205 Gen\u00e8ve, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Saudan","sequence":"additional","affiliation":[{"name":"Service de N\u00e9phrologie, D\u00e9partement de M\u00e9decine Interne, H\u00f4pitaux Universitaires de Gen\u00e8ve, 1205 Gen\u00e8ve, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1093\/ndt\/16.suppl_5.73","volume":"16","year":"2001","journal-title":"Nephrology Dialysis Transplantation"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-008-0811-4"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.00680207"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfq477"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1128\/CDLI.9.2.482-484.2002"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-006-9102-9"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s001340050957"},{"issue":"11","key":"8","doi-asserted-by":"crossref","first-page":"3581","DOI":"10.1097\/00003246-200011000-00001","volume":"28","year":"2000","journal-title":"Critical Care Medicine"},{"issue":"5","key":"9","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1177\/039139880502800505","volume":"28","year":"2005","journal-title":"International Journal of Artificial Organs"}],"container-title":["Case Reports in Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crin\/2011\/817414.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crin\/2011\/817414.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crin\/2011\/817414.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,15]],"date-time":"2019-06-15T09:05:22Z","timestamp":1560589522000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crin\/2011\/817414\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":9,"alternative-id":["817414","817414"],"URL":"https:\/\/doi.org\/10.1155\/2011\/817414","relation":{},"ISSN":["2090-6641","2090-665X"],"issn-type":[{"value":"2090-6641","type":"print"},{"value":"2090-665X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}