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Recently, a diffeomorphic version of the Demons algorithm was proposed. This provides the advantage of producing invertible displacement fields, which is a necessary condition for these to be physical. However, such methods are based on the matching of intensities and are not suitable for registering images with different contrast enhancement. In such cases, a registration method based on the local phase like the Morphons has to be used. In this paper, a diffeomorphic version of the Morphons registration method is proposed and compared to conventional Morphons, Demons, and diffeomorphic Demons. The method is validated in the context of radiotherapy for lung cancer patients on several 4D respiratory-correlated CT scans of the thorax with and without variable contrast enhancement.<\/jats:p>","DOI":"10.1155\/2011\/891585","type":"journal-article","created":{"date-parts":[[2010,12,8]],"date-time":"2010-12-08T19:35:51Z","timestamp":1291836951000},"page":"1-16","source":"Crossref","is-referenced-by-count":66,"title":["Diffeomorphic Registration of Images with Variable Contrast Enhancement"],"prefix":"10.1155","volume":"2011","author":[{"given":"Guillaume","family":"Janssens","sequence":"first","affiliation":[{"name":"Institute of Information and Communication Technologies, Electronics and Applied Mathematics (ICTEAM), Universit\u00e8 Catholique de Louvain (UCL), 1348 Louvain-la-Neuve, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Jacques","sequence":"additional","affiliation":[{"name":"Institute of Information and Communication 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