{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T16:01:53Z","timestamp":1761580913498,"version":"3.37.3"},"reference-count":19,"publisher":"Wiley","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Advances in Urology"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p><jats:italic>Background.<\/jats:italic>While tobacco use by a renal transplant recipient has been shown to negatively affect graft and patient survival, the effect of smoking on the part of the kidney donor remains unknown.<jats:italic>Methods.<\/jats:italic>29 smoking donors (SD) and their recipients (SD-R) as well as 71 non-smoking donors (ND) and their recipients (ND-R) were retrospectively reviewed. Preoperative demographics and perioperative variables including serum creatinine (Cr) and glomerular filtration rate (GFR) were calculated and stratified by amount of tobacco exposure in pack-years. Clinical outcomes were analyzed with a Student's<jats:italic>t<\/jats:italic>-test, chi-square, and multiple linear regression analysis ().<jats:italic>Results.<\/jats:italic>At most recent followup, SD-R's had a significantly smaller percent decrease in postoperative Cr than ND-R's (\u221257% versus \u221281%; ) and lower calculated GFR's (37.0 versus 53.0\u2009mL\/min per 1.73 m<jats:sup>2<\/jats:sup>; . SD's had a larger percent increase in Cr than ND's at most recent followup (57% versus 40%; ), with active smokers having a larger increase than those who quit, although this difference was not statistically significant (68% versus 52%; ).<jats:italic>Conclusions.<\/jats:italic>Use of tobacco by kidney donors is associated with decreased posttransplant renal function, although smoking cessation can improve outcomes. Kidneys from donors who smoke should be used with caution.<\/jats:p>","DOI":"10.1155\/2011\/929263","type":"journal-article","created":{"date-parts":[[2011,9,6]],"date-time":"2011-09-06T19:11:29Z","timestamp":1315336289000},"page":"1-5","source":"Crossref","is-referenced-by-count":25,"title":["Donor Smoking Negatively Affects Donor and Recipient Renal Function following Living Donor Nephrectomy"],"prefix":"10.1155","volume":"2011","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0527-0056","authenticated-orcid":true,"given":"Jonathan","family":"Heldt","sequence":"first","affiliation":[{"name":"Department of Urology, Loma Linda University Medical Center, Loma Linda, CA 92354, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Torrey","sequence":"additional","affiliation":[{"name":"Department of Urology, Loma Linda University Medical Center, Loma Linda, CA 92354, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Urology, Loma Linda University Medical Center, Loma Linda, CA 92354, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Baron","sequence":"additional","affiliation":[{"name":"Transplant Surgery, Loma Linda University Medical Center, Loma Linda, CA 92354, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Tenggardjaja","sequence":"additional","affiliation":[{"name":"Department of Urology, Loma Linda University Medical Center, Loma Linda, CA 92354, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin","family":"McLarty","sequence":"additional","affiliation":[{"name":"Department of Urology, Loma Linda University Medical Center, Loma Linda, CA 92354, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tekisha","family":"Lindler","sequence":"additional","affiliation":[{"name":"Department of Urology, Loma Linda University Medical Center, Loma Linda, CA 92354, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. 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