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We report the case of a young woman with chronic hepatitis C virus and multiple extrahepatic autoimmune diseases including Sj\u00f6gren syndrome and pernicious anemia who presented with subacute midline cerebellar syndrome and was found to have positive antiglutamic acid decarboxylase (GAD) antibody in the serum and cerebrospinal fluid. An extensive diagnostic workup to rule out neoplastic growths was negative, suggesting the diagnosis of nonparaneoplastic antiglutamic acid decarboxylase antibody-associated cerebellar ataxia as an additional extrahepatic manifestation of hepatitis C virus infection. The patient failed to respond to high-dose steroids and intravenous immunoglobulin. Treatment with the monoclonal antibody rituximab stabilized the disease. We postulate that anti-GAD associated ataxia could be an extrahepatic manifestation of HCV infection.<\/jats:p>","DOI":"10.1155\/2011\/975152","type":"journal-article","created":{"date-parts":[[2011,7,10]],"date-time":"2011-07-10T21:40:37Z","timestamp":1310334037000},"page":"1-4","source":"Crossref","is-referenced-by-count":1,"title":["Anti-Glutamic Acid Decarboxylase Antibody-Associated Ataxia as an Extrahepatic Autoimmune Manifestation of Hepatitis C Infection: A Case Report"],"prefix":"10.1155","volume":"2011","author":[{"given":"Amer","family":"Awad","sequence":"first","affiliation":[{"name":"Baton Rouge Neurology Associates, Baton Rouge General Medical Center, Baton Rouge, LA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olaf","family":"St\u00fcve","sequence":"additional","affiliation":[{"name":"Department of Neurology, The University of Texas Southwestern Medical Center, Dallas, TX, USA"},{"name":"Neurology Section, VA North Texas Health Care Systems, 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