{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T21:17:03Z","timestamp":1778707023304,"version":"3.51.4"},"reference-count":41,"publisher":"Wiley","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["555516\/2006-7"],"award-info":[{"award-number":["555516\/2006-7"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["575573\/2008-2"],"award-info":[{"award-number":["575573\/2008-2"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"name":"CT-AMAZONIA","award":["555516\/2006-7"],"award-info":[{"award-number":["555516\/2006-7"]}]},{"name":"CT-AMAZONIA","award":["575573\/2008-2"],"award-info":[{"award-number":["575573\/2008-2"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biomedicine and Biotechnology"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>Neurodevelopment as Gesell development scores (GDSs) in relation to mercury exposure in infants (&lt;6 months of age) of one urban center and two rural villages, respectively, of fisherman and cassiterite miners. Mean total hair-Hg (HHg) concentrations of infants from Itapu\u00e3 (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mn>3.95<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>1.8<\/mml:mn><\/mml:mrow><\/mml:math>\u2009ppm) were statistically (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.0001<\/mml:mn><\/mml:mrow><\/mml:math>) different from those of infants from Porto Velho (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mn>3.84<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>5.5<\/mml:mn><\/mml:mrow><\/mml:math>\u2009ppm) and Bom Futuro (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mn>1.85<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>0.9<\/mml:mn><\/mml:mrow><\/mml:math>\u2009ppm). Differences in vaccine coverage among these populations resulted in significantly higher (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.0001<\/mml:mn><\/mml:mrow><\/mml:math>) mean ethylmercury (EtHg) exposure in urban infants (150\u2009\u03bcg) than in infants from either village (41.67\u2009\u03bcg, Itapu\u00e3; 42.39\u2009\u03bcg, Bom Futuro). There was an inverse significant (Spearman<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mi>r<\/mml:mi><mml:mo>=<\/mml:mo><mml:mo>\u2212<\/mml:mo><mml:mn>0.2300<\/mml:mn><\/mml:mrow><\/mml:math>;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.0376<\/mml:mn><\/mml:mrow><\/mml:math>) correlation between HHg and GDS for infants from Porto Velho, but not for the rural infants from Bom Futuro (Spearman<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mi>r<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.1336<\/mml:mn><\/mml:mrow><\/mml:math>;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.0862<\/mml:mn><\/mml:mrow><\/mml:math>) and Itapu\u00e3 (Spearman<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mi>r<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.1666<\/mml:mn><\/mml:mrow><\/mml:math>;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.5182<\/mml:mn><\/mml:mrow><\/mml:math>). Logistic regression applied to variables above or below the median GDS showed that EtHg exposure (estimated<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mtext>probability<\/mml:mtext><mml:mo>=<\/mml:mo><mml:mo>\u2212<\/mml:mo><mml:mn>0.0157<\/mml:mn><\/mml:mrow><\/mml:math>;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.0070<\/mml:mn><\/mml:mrow><\/mml:math>) and breastfeeding score (estimated<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mtext>probability<\/mml:mtext><mml:mo>=<\/mml:mo><mml:mo>\u2212<\/mml:mo><mml:mn>0.0066<\/mml:mn><\/mml:mrow><\/mml:math>;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.0536<\/mml:mn><\/mml:mrow><\/mml:math>) score were significantly associated with GDS.<jats:italic>Conclusion<\/jats:italic>. In nurslings whose mothers are exposed to different levels of fish-MeHg (HHg), a higher score of neurological development at six months was negatively associated with exposure to additional TCV-EtHg. Results should be interpreted with caution because of unaccounted variables.<\/jats:p>","DOI":"10.1155\/2012\/132876","type":"journal-article","created":{"date-parts":[[2012,4,26]],"date-time":"2012-04-26T17:00:36Z","timestamp":1335459636000},"page":"1-9","source":"Crossref","is-referenced-by-count":39,"title":["Neurodevelopment of Amazonian Infants: Antenatal and Postnatal Exposure to Methyl- and Ethylmercury"],"prefix":"10.1155","volume":"2012","author":[{"given":"Jos\u00e9 G.","family":"D\u00f3rea","sequence":"first","affiliation":[{"name":"Department of Nutrition, University of Bras\u00edlia, 70919-970 Bras\u00edlia, DF, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rejane C.","family":"Marques","sequence":"additional","affiliation":[{"name":"Federal University of Rio de Janeiro, Campus Maca\u00e9, 27971-550 Rio de Janeiro, RJ, 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