{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T20:54:40Z","timestamp":1790024080207,"version":"4.0.1"},"reference-count":18,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,12,2]],"date-time":"2012-12-02T00:00:00Z","timestamp":1354406400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic and Therapeutic Endoscopy"],"published-print":{"date-parts":[[2012,12,2]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. i-scan is a software-driven technology that allows modifications of sharpness, hue, and contrast to enhance mucosal imaging. It uses postimage acquisition software with real-time mapping technology embedded in the endoscopic processor. <jats:italic>Aims<\/jats:italic>. To review applications of i-scan technology in clinical endoscopic practice. <jats:italic>Methods<\/jats:italic>. This is a case series of 20 consecutive patients who underwent endoscopic procedures where i-scan image enhancement algorithms were applied. The main outcome measures were to compare mucosal lesions with high-definition white light endoscopy (HD-WLE) and i-scan image enhancement for the application of diagnostic sampling and therapy. <jats:italic>Results<\/jats:italic>. 13 cases involving the upper GI tract and 7 cases of the lower GI tract are included. For upper GI tract pathology i-scan assisted in diagnosis or therapy of Barrett\u2019s esophagus with dysplasia, esophageal adenocarcinoma, HSV esophagitis, gastric MALT lymphoma, gastric antral intestinal metaplasia with dysplasia, duodenal follicular lymphoma, and a flat duodenal adenoma. For lower GI tract pathology i-scan assisted in diagnosis or therapy of right-sided serrated adenomas, flat tubular adenoma, rectal adenocarcinoma, anal squamous cell cancer, solitary rectal ulcer, and radiation proctitis. <jats:italic>Conclusions<\/jats:italic>. i-scan imaging provides detailed topography of mucosal surfaces and delineates lesion edges, which can directly impact endoscopic management.<\/jats:p>","DOI":"10.1155\/2012\/193570","type":"journal-article","created":{"date-parts":[[2012,12,2]],"date-time":"2012-12-02T21:15:11Z","timestamp":1354482911000},"page":"1-9","source":"Crossref","is-referenced-by-count":19,"title":["Use of i-scan Endoscopic Image Enhancement Technology in Clinical Practice to Assist in Diagnostic and Therapeutic Endoscopy: A Case Series and Review of the Literature"],"prefix":"10.1155","volume":"2012","author":[{"given":"Shawn","family":"Hancock","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology, School of 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