{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T23:34:23Z","timestamp":1648769663564},"reference-count":13,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Immunology"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>We describe a girl, now 9 years of age, with chronic idiopathic thrombocytopenic purpura, persistent nonmalignant lymphadenopathy, splenomegaly, recurrent infections, and autoimmune hemolytic anemia. Her symptoms partly fit the definitions of both autoimmune lymphoproliferative syndrome (ALPS) and common variable immunodeficiency disorders (CVIDs). Genetic analysis showed no abnormalities in the ALPS-genes<jats:italic>FAS, FASLG<\/jats:italic>, and<jats:italic>CASP10<\/jats:italic>. The CVID-associated<jats:italic>TACI<\/jats:italic>gene showed a homozygous polymorphism (Pro251Leu), which is found also in healthy controls.<\/jats:p>","DOI":"10.1155\/2012\/196417","type":"journal-article","created":{"date-parts":[[2012,11,21]],"date-time":"2012-11-21T21:00:44Z","timestamp":1353531644000},"page":"1-6","source":"Crossref","is-referenced-by-count":0,"title":["A Girl with Autoimmune Cytopenias, Nonmalignant Lymphadenopathy, and Recurrent Infections"],"prefix":"10.1155","volume":"2012","author":[{"given":"Marjolein A. C.","family":"Mattheij","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Jeroen Bosch Hospital, P.O. Box 90153, 5200 ME 's-Hertogenbosch, The Netherlands"},{"name":"University Medical Centre Antwerp, Antwerp, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellen J. H.","family":"Schatorj\u00e9","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Jeroen Bosch Hospital, P.O. Box 90153, 5200 ME 's-Hertogenbosch, The Netherlands"},{"name":"Radboud University Medical Centre Nijmegen, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugenie F. A.","family":"Gemen","sequence":"additional","affiliation":[{"name":"Laboratory for Clinical Chemistry and Hematology, Jeroen Bosch Hospital, P.O. Box 90153, 5200 ME 's-Hertogenbosch, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisette","family":"van de Corput","sequence":"additional","affiliation":[{"name":"Department of Medical Immunology, University Medical Center Utrecht, P.O. Box 85500, Utrecht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peet T. G. A.","family":"Nooijen","sequence":"additional","affiliation":[{"name":"Department of Pathology, Jeroen Bosch Hospital, P.O. 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