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The mechanisms that regulate host inflammatory responses and tissue injury are incompletely understood. Accumulating evidence suggests that hyaluronan and its interaction with its cell surface receptor CD44 plays an important role in mediating pathogenic mechanisms in SLE. This paper discusses the putative mechanisms through which hyaluronan and CD44 contribute to the pathogenesis of SLE, with particular emphasis on lupus nephritis.<\/jats:p>","DOI":"10.1155\/2012\/207190","type":"journal-article","created":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T21:00:40Z","timestamp":1343854840000},"page":"1-9","source":"Crossref","is-referenced-by-count":10,"title":["The Role of Hyaluronan and CD44 in the Pathogenesis of Lupus Nephritis"],"prefix":"10.1155","volume":"2012","author":[{"given":"Susan","family":"Yung","sequence":"first","affiliation":[{"name":"Department of Medicine, University of Hong Kong, Room 302 New Clinical Building, Queen Mary Hospital, Pokfulam, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tak Mao","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Hong Kong, Room 302 New Clinical Building, Queen Mary Hospital, Pokfulam, Hong 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