{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:11:12Z","timestamp":1788869472017,"version":"build-2803163510"},"reference-count":27,"publisher":"Wiley","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"crossref","award":["APQ001562-11"],"award-info":[{"award-number":["APQ001562-11"]}],"id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"crossref","award":["APQ001562-11"],"award-info":[{"award-number":["APQ001562-11"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>\n                    This case report describes an atypical clinical presentation of visceral leishmaniasis affecting the digestive tract and causing malabsorption syndrome in a patient without recognized immunosuppressive condition. After appropriate treatment for the classical visceral form of the disease, diarrhea persisted as the main symptom and massive infection by\n                    <jats:italic>Leishmania<\/jats:italic>\n                    was detected by histopathology analysis of the duodenal mucosa.\n                    <jats:italic>Schistosoma mansoni<\/jats:italic>\n                    coinfection was also confirmed and treated without impact on diarrhea. New course of amphotericin B finally led to complete improvement of diarrhea. Atypical visceral leishmaniasis involving the gastrointestinal tract is well recognized in HIV coinfection but very rare in immunocompetent patients. The factors determining the control or evolution of the\n                    <jats:italic>Leishmania<\/jats:italic>\n                    infection have not been completely identified. This case stresses the importance of atypical symptoms and the unusual location of visceral leishmaniasis, not only in immunodepressed patients, and raises the possible influence of chronic infection by\n                    <jats:italic>S. mansoni<\/jats:italic>\n                    reducing the immune response to\n                    <jats:italic>Leishmania<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1155\/2012\/240512","type":"journal-article","created":{"date-parts":[[2012,11,18]],"date-time":"2012-11-18T16:00:18Z","timestamp":1353254418000},"page":"1-4","source":"Crossref","is-referenced-by-count":9,"title":["Dyarrheal Syndrome in a Patient Co-Infected with\n                    <i>Leishmania infantum<\/i>\n                    and\n                    <i>Schistosoma mansoni<\/i>"],"prefix":"10.1155","volume":"2012","author":[{"given":"Gl\u00e1ucia Fernandes","family":"Cota","sequence":"first","affiliation":[{"name":"Hospital Eduardo de Menezes, Funda\u00e7\u00e3o Hospitalar do Estado de Minas Gerais (Fhemig), Rua Dr Cristiano Resende, 2213, 30622-020 Belo Horizonte, MG, Brazil"},{"name":"Laborat\u00f3rio de Pesquisas Cl\u00ednicas, Centro de Pesquisas Ren\u00e9 Rachou, Instituto Oswaldo Cruz-FIOCRUZ, Avenida Augusto de Lima, 1715, 30190-002 Belo Horizonte, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciana In\u00e1cia","family":"Gomes","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Pesquisas Cl\u00ednicas, Centro de Pesquisas Ren\u00e9 Rachou, Instituto Oswaldo Cruz-FIOCRUZ, Avenida Augusto de Lima, 1715, 30190-002 Belo Horizonte, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna Fernandes","family":"Pinto","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Pesquisas Cl\u00ednicas, Centro de Pesquisas Ren\u00e9 Rachou, Instituto Oswaldo Cruz-FIOCRUZ, Avenida Augusto de Lima, 1715, 30190-002 Belo Horizonte, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna R.","family":"Santos-Oliveira","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio Interdisciplinar de Pesquisas M\u00e9dicas, Instituto Oswaldo Cruz-FIOCRUZ, Avenida Brasil, 4365, 21040-360 Manguinhos, Rio de Janeiro, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alda Maria","family":"Da-Cruz","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio Interdisciplinar de Pesquisas M\u00e9dicas, Instituto Oswaldo Cruz-FIOCRUZ, Avenida Brasil, 4365, 21040-360 Manguinhos, Rio de Janeiro, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mois\u00e9s Salgado","family":"Pedrosa","sequence":"additional","affiliation":[{"name":"Hospital Eduardo de Menezes, Funda\u00e7\u00e3o Hospitalar do Estado de Minas Gerais (Fhemig), Rua Dr Cristiano Resende, 2213, 30622-020 Belo Horizonte, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wagner Luiz","family":"Tafuri","sequence":"additional","affiliation":[{"name":"Departamento de Patologia Geral, Instituto de Ci\u00eancias Biol\u00f3gicas, Universidade Federal de Minas Gerais, Avenida Ant\u00f4nio Carlos, 6627, 31270-901 Belo Horizonte, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Rabello","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Pesquisas Cl\u00ednicas, Centro de Pesquisas Ren\u00e9 Rachou, Instituto Oswaldo Cruz-FIOCRUZ, Avenida Augusto de Lima, 1715, 30190-002 Belo Horizonte, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","series-title":"A. Normas e Manuais T\u00e9cnicos","year":"2011"},{"issue":"4","key":"2","first-page":"233","volume":"16","year":"2008","journal-title":"Infezioni in Medicina"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e32830e6fdb"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1086\/318135"},{"issue":"1","key":"5","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1093\/clinids\/19.1.48","volume":"19","year":"1994","journal-title":"Clinical Infectious Diseases"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2007.04.026"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2005.027029"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jim.2004.05.009"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001198"},{"issue":"6","key":"10","first-page":"309","volume":"25","year":"2006","journal-title":"Indian Journal of Gastroenterology"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.medmal.2005.11.013"},{"issue":"6367","key":"12","volume":"286","year":"1983","journal-title":"British Medical Journal"},{"issue":"3","key":"13","first-page":"258","volume":"66","year":"2003","journal-title":"Acta Gastro-Enterologica Belgica"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1179\/136485906X112149"},{"issue":"8348","key":"15","first-page":"476","volume":"2","year":"1983","journal-title":"The Lancet"},{"issue":"6400","key":"16","volume":"287","year":"1983","journal-title":"British Medical Journal"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-2896.2004.00187.x"},{"issue":"7","key":"18","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1590\/S0074-02762011000700012","volume":"106","year":"2011","journal-title":"Memorias do Instituto Oswaldo Cruz"},{"issue":"1","key":"19","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1590\/S0100-879X2004000100018","volume":"37","year":"2004","journal-title":"Brazilian Journal of Medical and Biological Research"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2007.07.004"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2006.051319"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1086\/509808"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3024.1999.00213.x"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/dxg012"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2006.00431.x"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830260633"},{"issue":"1","key":"27","first-page":"339","volume":"101","year":"2006","journal-title":"Memorias do Instituto Oswaldo Cruz"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2012\/240512.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2012\/240512.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2012\/240512.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T22:50:05Z","timestamp":1497999005000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crim\/2012\/240512\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":27,"alternative-id":["240512","240512"],"URL":"https:\/\/doi.org\/10.1155\/2012\/240512","relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"value":"1687-9627","type":"print"},{"value":"1687-9635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}